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Alternative structural projections:

8-[DY-547]-AET-cAMP

8- (2- [DY-547]- aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-[DY-547]-AET-cAMP ), sodium salt
cyclic AMP conjugated with the fluorescent dye DY-547
Cat. No.: D 109
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: D 109-001
Unit: 0.1 µmol / ~0.1 mg
$240.00
For other salt forms please inquire. Fluorescent cAMP analogue (λexc 557 nm, λem 574 nm) e.g. for research focussed on activation studies of HCN2 channels and other cAMP-responsive binding proteins Detailed technical information available. Reference: Kusch et al., Neuron, 67, 75 - 85 (2010).
Cat. No. D 109
CAS number [pending]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₄₂H₄₉N₈O₁₃PS₃ · Na₂
Molecular weight [g/mol] 1047,1
Modifications 8-cAMP
Target PKA (cAK) Activator
Excitation max [nm] 557
Emission max [nm] 574
Absorption max [nm] 559
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 150000
Solvent for UV data EtOH
  • 1. Kusch J., Thon S., Schulz E., Biskup C., Nache V., Zimmer T., Seifert R., Schwede F.Benndorf K., Nat. Chem. Biol., 8, 162 - 169 (2012), "How Subunits Cooperate in cAMP-induced Activation of Homotetrameric HCN2 Channels"
  • 2. Kusch J., Biskup C., Thon S., Schulz E., Nache V., Zimmer T., Schwede F.Benndorf K., Neuron, 67, 75 - 85 (2010), "Interdependence of Receptor Activation and Ligand Binding in HCN2 Pacemaker Channels"