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Alternative structural projections:

8-Br-PET-cGMP

8- Bromo- β- phenyl- 1, N²- ethenoguanosine- 3', 5'-cyclic monophosphate ( 8-Br-PET-cGMP ), sodium salt

Cat. No.: P 003
    
CAS No.: [144510-04-3]
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Product Name Price (net) Qty
Cat. No.: P 003-10
Unit: 10 µmol / ~5.5 mg
$204.00

For other salt forms or metabolites please inquire. Potent membrane-permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase while only a poor stimulator of type II. Common agonists such as 8-Br-cGMP (Cat. No. B 004) or 8-pCPT-cGMP (Cat. No. C 009) mainly activate kinase subtypes I α and II. 8-Br-PET-cGMP is one of the best activators of isozyme I β and one of the best cyclic nucleotide muscle relaxants. Detailed technical information and updated reference list available. Reference: Sekhar et al., Mol. Pharmacol., 42, 103 - 108 (1992).

Cat. No. P 003
CAS number [144510-04-3]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₈H₁₄BrN₅O₇P · Na
Molecular weight [g/mol] 546,2
Modifications 8-cGMP
Target PKG (cGK) Activator
Lipophilicity 2.83
Absorption max [nm] 256
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 40000
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