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Alternative structural projections:

8-Br-cGMP

8- Bromoguanosine- 3', 5'- cyclic monophosphate ( 8-Br-cGMP ), sodium salt
PKG Agonist
Cat. No.: B 004
    
CAS No.: [51116-01-9]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: B 004-50
Unit: 50 µmol / ~22 mg
$50.00
Specially purified, typical fluorescent impurities removed. For other salt forms or metabolites of 8-Br-cGMP please inquire. Activator of cGMP-dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cyclic GMP agonist). Increased metabolic stability compared to cGMP, but not completely stable as often stated. 8-pCPT-cGMP (Cat. No. C 009), a highly membrane-permeant and metabolically resistant cGMP-agonist seems to be superior for most applications. Detailed technical information and reference list available. Reference: Rapoport et al., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982).
Cat. No. B 004
CAS number [51116-01-9]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀BrN₅O₇P · Na
Molecular weight [g/mol] 446,1
Modifications 8-cGMP
Target PKG (cGK) Activator
Lipophilicity 1.17
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200
  • 1. Jäger R., Russwurm C., Schwede F., Genieser H.-G., Koesling D.Russwurm M., J. Biol. Chem., 287, 1210 - 1219 (2012), "Activation of PDE10 and PDE11 Phosphodiesterases"
  • 2. Kurauchi Y., Hisatsune A., Isohama Y., Sawa T., Akaike T., Shudo K.Katsuki H., J. Neurochem., 116, 323 - 333 (2011), "Midbrain Dopaminergic Neurons Utilize Nitric Oxide/cyclic GMP Signaling to Recruit ERK that Links Retinoic Acid Receptor Stimulation to Up-regulation of BDNF"
  • 3. Werner K., Schwede F., Genieser H.-G., Geiger J.Butt E., Naunyn Schmiedebergs Arch. Pharmacol., 384, 169 - 176 (2011), "Quantification of cAMP and cGMP Analogs in Intact Cells: Pitfalls in Enzyme Immunoassays for Cyclic Nucleotides"
  • 4. Jäger R., Schwede F., Genieser H.-G., Koesling D.Russwurm M., Br. J. Pharmacol., 161, 1645 - 1660 (2010), "Activation of PDE2 and PDE5 cy Specific GAF Ligands: Delayed Activation of PDE5"
  • 5. Desch M., Schinner E., Kees F., Hofmann F., Seifert R.Schlossmann J., FEBS Lett., 584, 3979 - 3984 (2010), "Cyclic Cytidine 3',5'-Monophosphate (cCMP) Signals via cGMP Kinase I"
  • 6. Voisin P.Bernard M., J. Neurochem., 110, 318 - 327 (2009), "Cyclic AMP-dependent Activation of Rhodopsin Gene Transcription in Cultured Retinal Precursor Cells of Chicken Embryo"
  • 7. Matthiesen K.Nielsen J., Biochem. J., 423, 401 - 409 (2009), "Binding of Cyclic Nucleotides to Phosphodiesterase 10A and 11A GAF Domains Does Not Stimulate Catalytic Activity"
  • 8. Poppe H., Rybalkin S. D., Rehmann H., Hinds T. R., Tang X.-B., Christensen A. E., Schwede F., Genieser H.-G., Bos J. L., Doeskeland S. O., Beavo J. A.Butt E., Nature Methods, 5, 277 - 278 (2008), "Cyclic Nucleotide Analogs as Probes of Signaling Pathways"
  • 9. Sawa T., Zaki M. H., Okamoto T., Akuta T., Tokutomi Y., Kim-Mitsuyama S., Ihara H., Kobayashi A., Yamamoto M., Fujii S., Arimoto H.Akaike T., Nature Chem. Biol., 3, 727 - 735 (2007), "Protein S-guanylation by the Biological Signal 8-nitroguanosine 3',5'-cyclic Monophosphate"
  • 10. Gonzalez-Iglesias A. E., Jiang Y., Tomic M., Kretschmannova K., Andric S. A., Zemkova H.Stojilkovic S. S., Mol. Endocrinol., 20, 2231 - 2246 (2006), "Dependence of Electrical Activity and Calcium Influx-controlled Prolactin Release on Adenylyl Cyclase Signaling Pathway in Pituitary Lactotrophs"
  • 11. Lotfi S., Li Z., Sun J., Zuo Y., Lamm P. P., Kang Y., Rahimi M., Islam D., Wang P., Gaisano H. Y.Jin T., Endocrinology, 147, 3727 - 3736 (2006), "Role of Excange Protein Directly Activated by cyclic Adenosine 5'-monophosphate (Epac) Pathway in Regulating Proglucagon Gene Expression in Intestinal Endocrine L Cells"
  • 12. Song X. J., Wang Z. B., Gan Q.Walters E. T., J. Neurophysiol., 95, 479 - 492 (2006), "cAMP and cGMP Contribute to Sensory Neuron Hyperexcitability and Hyperalgesia in Rats with Dorsal Root Ganglia Compression"
  • 13. Mewe M., Bauer C. K., Müller D.Middendorff R., Endocrinology, 147, 2051 - 2062 (2006), "Regulation of Spontaneous Contractile Activity in the Bovine Epididymal Duct by Cyclic Guanosine 5'- monophosphate-dependent Pathways"
  • 14. Sergeant G. P., Johnston L., McHale N. G., Thornbury K. D.Hollywood M. A., J. Physiol.-London, 574, 167 - 181 (2006), "Activation of the cGMP/PKG Pathway Inhibits Electrical Activity in Rabbit Urethral Interstitial Cells of Cajal by Reducing the Spatial Spread of Ca2+ Waves"
  • 15. Zhang M. J., Hong H., Zhou B., Jin S., Wang C., Fu M., Wang S.Xia G., J. Endocrinol., 189, 493 - 507 (2006), "The Expression of Atrial Natriuretic Peptide in the Oviduct and its Functions in Pig Spermatozoa"
  • 16. Brown R. L., Strassmaier T., Brady J. D.Karpen J. W., Curr. Pharmaceut. Design, 12, 3597 - 3613 (2006), "The Pharmacology of Cyclic Nucleotide-Gated Channels: Emerging from the Darkness"
  • 17. Jao Y., Hiramatsu N., Zhu Y., Morioka T., Takeda M., Oite T.Kitamura M., J. Am. Soc. Nephrol., 16, 58 - 67 (2005), "Nitric Oxide-mediated Regulation of Connexin43 Expression and Gap Junctional Intercellular Communication in Mesangial Cells"
  • 18. Abdallah Y., Gkatzoflia A., Pieper H., Zoga E., Walther S., Kasseckert S., Schäfer M., Schlüter K. D., Piper H. M.Schäfer C., Cardiovasc. Res., 66, 123 - 131 (2005), "Mechanism of cGMP-mediated Protection in a Cellular Model of Myocardial Reperfusion Injury"
  • 19. Muzaffar S., Shukla N., Angelini G. D.Jeremy J. Y., Brit. J. Pharmacol., 145, 688 - 697 (2005), "Prednisolone Augments Superoxide Formation in Porcine Pulmonary Artery Endothelial Cells Through Differential Effects on the Expression of Nitric Oxide Synthase and NADPH Oxidase"
  • 20. Puzzo D., Vitolo O., Trinchese F., Jacob J. P., Palmeri A.Arancio O., J. Neurosci., 25, 6887 - 6897 (2005), "Amyloid-beta Peptide Inhibits Activation of the Nitric Oxide/cGMP/cAMP-responsive Element-binding Protein Pathway During Hippocampal Synaptic Plasticity"
  • 21. Lohmann S. M.Walter U., Frontiers Biosci., 10, 1313 - 1328 (2005), "Tracking Functions of cGMP-dependent Protein Kinase"
  • 22. Matchkov V. V., Aalkjaer C.Nilsson H., J. Gen. Physiol., 123, 121 - 134 (2004), "A Cyclic GMP-dependent Calcium-activated Chloride Current in Smooth-muscle Cells from Rat Mesenteric Resistance Arteries"
  • 23. Ivins J. K., Parry M. K.Long D. A., J. Neurosci., 5, 1212 - 216 (2004), "A Novel cAMP-dependent Pathway Activates Neuronal Integrin Function in Retinal Neurons"
  • 24. Piper A. S.Large W. A., J. Physiol., 555, 397 - 408 (2004), "Single cGMP-activated Ca2+dependent Cl-channels in Rat Mesenteric Artery Smooth Muscle Cells"
  • 25. Chan S. H. H., Chang K. F., Ou C. C.Chan J. Y. H., Mol. Pharmacol., 65, 319 - 325 (2004), "Nitric Oxide Regulates c-fos Expression in Nucleus Tractus Solitarii Induced by Baroreceptor Activation via cGMP-dependent Protein Kinase and cAMP Response Element-binding Phosphorylation"
  • 26. Taylor M. S., Okwuchukwuasanya C., Nickl C. K., Tegge W., Brayden J. E.Dostmann W. R. G., Mol. Pharmacol., 65, 1111 - 1119 (2004), "Inhibition of cGMP-dependent Protein Kinase by the Cell-permeable Peptide DT-2 Reveals a Novel Mechanism of Vasoregulation"
  • 27. Genieser H.-G., Bos J. L., Christensen A. E., Doeskeland S. O., Havemann U., Manzau U., Rehmann H.Schwede F., Poster #THP016 Montreal, 12, 0 - 0 (2004), "Analogues of Cyclic AMP to Distinguish Between PKA and Epac"
  • 28. Dyachok O.Gylfe E., J. Biol. Chem., 279, 45455 - 45461 (2004), "Ca2+-induced Ca2+ Release via Inositol 1,4,5-triphosphate Receptors is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic Beta-cells"
  • 29. Gambaryan S., Geiger J., Schwarz U. R., Butt E., Begonja A., Obergfell A.Walter U., Blood, 103, 2593 - 2600 (2004), "Potent Inhibition of Human Platelets by cGMP Analogs Independent of cGMP-dependent Protein Kinase"
  • 30. Barnstable C. J., Wei J. Y.Han M. H., Neurochem. Int., 45, 875 - 884 (2004), "Modulation of Synaptic Function by cGMP and cGMP-gated Cation Channels"
  • 31. Podda M. V., Marcocci M. E., Oggiano L., D'Ascenzo M., Tolu E., Palamara A. T., Azzena G. B.Grassi C., Eur. J. Neurosci., 20, 2124 - 2132 (2004), "Nitric Oxide Increases the Spontaneous Firing Rate of Rat Medial Vestibular Nucleus Neurons in Vitro via a Cyclic GMP-mediated PKG-independent Mechanism"
  • 32. Chen L., Wang P., Andrade C. F., Zhao I. Y., Dube P. E., Brubaker P. L., Liu M.Jin T., FEBS J., 272, 2746 - 2759 (2004), "PKA Independent and Cell Type Specific Activation of the Expression of Caudal Homeobox Gene Cdx-2 by cyclic AMP"
  • 33. Jensen B. O., Selheim F., Doeskeland S. O., Gear A. R. L.Holmsen H., Blood, 104, 2775 - 2782 (2004), "Protein Kinase A Mediates Inhibition of the Thrombin-Induced Platelet Shape Change by Nitric Oxide"
  • 34. Velardez M. O., Benitez A. H., Cabilla J. P., Bodo C. C. A.Duvilanski B. H., Eur. J. Endocrinol., 148, 89 - 97 (2003), "Nitric Oxide Decreases the Production of Inositol Phosphates Stimulated by Angiotensin II and Thyrotropin-releasing Hormone in Anterior Pituitary Cells"
  • 35. Hagen V., Frings S., Wiesner B., Helm S., Kaupp U. B.Bendig J., Chembiochem., 4, 434 - 442 (2003), "[7-(Dialkylamino)Coumarin-4-yl]Methyl-Caged Compounds as Ultrafast and Effective Long-wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides"
  • 36. Christensen A. E.Doeskeland S. O., Handbook of Cell Signaling Academic Press/Elsevier Science San Diego CA, 2, 549 - 554 (2003), "Cyclic Nucleotide Analogs as Tools to Investigate Cyclic Nucleotide Signaling"
  • 37. Bland R. D., Ling C. Y., Albertine K. H., Carlton D. P., MacRitchie A. J., Day R. W.Dahl M. J., Am. J. Physiol.-Lung Cell Mol. Physiol., 285, 76 - 85 (2003), "Pulmonary Vascular Dysfunction in Preterm Lambs with Chronic Lung Disease"
  • 38. Peluso J. J., J. Steroid. Biochem. Mol. Biol., 85, 167 - 173 (2003), "Progesterone as a Regulator of Granulosa Cell Viability"
  • 39. Deng W., Parbhu-Patel A., Meyer D. J.Baker D. A., Biochem. J., 374, 559 - 565 (2003), "The Role of Two Novel Regulatory Sites in the Activation of the cGMP-dependent Protein Kinase from Plasmodium Falciparum"
  • 40. Schmidtko A., Ruth P., Geisslinger G.Tegeder I., Nitric Oxide-Biol. Chem., 8, 89 - 94 (2003), "Inhibition of Cyclic Guanosine 5'-Monophosphate-dependent Protein Kinase 1 (PKG-1) in Lumbar Spinal Cord Reduces Formalin-induced Hyperalgesia and PKG Upregulation"
  • 41. West G. A., Meno J. R., Nguyen T.-S. K., Ngai A. C., Simard J. M.Winn H. R., J. Cardiovasc. Pharmacol., 41, 444 - 451 (2003), "cGMP-dependent and not cAMP-dependent Kinase is Required for Adenosine-induced Dilation of Intracerebral Arterioles"
  • 42. Gerzanich V., Ivanov A., Ivanova S., Yang J. B., Zhou H., Dong Y. F.Simard J. M., Circ. Res., 93, 805 - 812 (2003), "Alternative Splicing of cGMP-dependent Protein Kinase 1 in Angiotensin-hypertension - Novel Mechanism for Nitrate Tolerance in Vascular Smooth Muscle"
  • 43. Wyatt T. A., Forget M. A.Sisson J. H., Am. J. Pathol., 163, 1157 - 1166 (2003), "Ethanol stimulates Ciliary Beating by Dual Cyclic Nucleotide Kinase Activation in Bovine Bronchial Epithelial Cells"
  • 44. Gao Y., Dhanakoti S., Trevino E. M., Sander F. C., Portugal A. M.Raj J. U., Am. J. Physiol.-Lung Cell. Mol. Physiol., 285, 611 - 618 (2003), "Effect of Oxygen on Cyclic GMP-dependent Protein Kinase-mediated Relaxation in Ovine Fetal Pulmonary Arteries and Veins"
  • 45. Jernigan N. L., Walker B. R.Resta T. C., Am. J. Physiol.-Lung Cell. Mol. Physiol., 285, 634 - 642 (2003), "Pulmonary PKG-1 is Upregulated Following Chronic Hypoxia"
  • 46. Miyoshi K., Kawakami N., Horio S.Fukui H., Methods Find. Exp. Clin. Pharmacol., 25, 343 - 347 (2003), "Inhibition of Histamine hi Receptor Downregulation by KT5823, a Protein Kinase G Inhibitor"
  • 47. Giordano D., Magaletti D. M., Clark E. A.Beavo J. A., J. Immunol., 171, 6421 - 6430 (2003), "Cyclic Nucleotides Promote Monocyte Differentiation Toward a DC-SGN+ (CD209) Intermediate Cell and Impair Differentiation into Dendritic Cells"
  • 48. Langer M., Luttecke D.Schlüter K.-D., Pflugers Arch., 447, 289 - 297 (2003), "Mechanism of the Positive Contractile Effect of Nitric Oxide on Rat Ventricular Cardiomyocytes with Positive Force/Frequency Relatonship"
  • 49. Kiemer A. K., Bildner N., Weber N. C.Vollmar A. M., Endocrinology, 144, 802 - 812 (2003), "Characterization of Heme Oxygenase 1 (Heat Shock Protein 32) Induction by Atrial Natriuretic Peptide in Human Endothelial Cells"
  • 50. Lin M. J., Su M. C., Tan C. T., Su C. C., Li S. Y., Lin R. H., Lin-Shiau S. Y., Hung C. C.Lazarowski E. R., Hear. Res., 178, 52 - 58 (2003), "The Effect of L-arginine on Slow Motility of Mammalian Outer Hair Cell"
  • 51. Nishiyama M., Hoshimo A., Tsai L., Henley J. R., Goshima Y., Tessier-Lavigne M., Poo M.-M.Hong K., Nature, 423, 990 - 995 (2003), "Cyclic AMP/GMP-dependent Modulation of Ca2+ Channels Sets the Polarity of Nerve Growth-cone Turning"
  • 52. Steiner A. A., Antunes-Rodrigues J.Branco L. G. S., Brain Res., 944, 135 - 145 (2002), "Role of Preoptic Second Messenger Systems (cAMP and cGMP) in the Febrile Response"
  • 53. Wegener J. W., Nawrath H., Wolfsgruber W., Kühbandner S., Werner C., Hofmann F.Feil R., Circ. Res., 90, 18 - 20 (2002), "cGMP-dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium"
  • 54. Wei J.-Y., Jin X. T., Cohen E. D., Daw N. W.Barnstable C. J., Brain Res., 927, 42 - 54 (2002), "cGMP-induced Presynaptic Depression and Postsynaptic Facilitation at Glutamatergic Synapses in Visual Cortex"
  • 55. Salowe S. P., Wiltsie J., Liberator P. A.Donald R. G. K., Biochemistry, 41, 4385 - 4391 (2002), "The Role of a Parasite-Specific Allosteric Site in the Distinctive Activation Behavior of Eimeria tenella cGMP-Dependent Protein Kinase"
  • 56. Wu S. N., Lo Y. K., Chen C. C., Li H. F.Chiang H. T., Biochem. Pharmacol., 63, 199 - 206 (2002), "Inhibitory Effect of the Plant-Extract Osthole on L-Type Calcium Current in NG108-15 Neuronal Cells"
  • 57. Silva J. M.Lewis D. L., Pflugers Arch., 443, 671 - 675 (2002), "Nitric Oxide Enhances Ca2+-dependent K+ Channel Activity in Rat Carotid Body Cells"
  • 58. Begum N., Sandu O. A.Duddy N., Diabetes, 51, 2256 - 2263 (2002), "Negative Regulation of Rho Signaling by Insulin and its Impact on Actin Cytoskeleton Organization in Vascular Smooth Muscle Cells - Role of Nitric Oxide and Cyclic Guanosine Monophosphate Signaling Pathways"
  • 59. Gill R. K., Saksena S., Syed I. A., Tyagi S., Alrefai W. A., Malakooti J., Ramaswamy K.Dudeja P. K., Am. J. Physiol.-Gastroint. Liver Physiol., 283, 747 - 756 (2002), "Regulation of NHE3 by Nitric Oxide in Caco-2 Cells"
  • 60. Shimoda L. A., Welsh L. E.Pearse D. B., Am. J. Physiol.-Lung Cell. Mol. Physiol., 283, 297 - 304 (2002), "Inhibition of Inwardly Rectifying K+ Channels by cGMP in Pulmonary Vascular Endothelial Cells"
  • 61. Saksena S., Gill R. K., Syed I. A., Tyagi S., Alrefai W. A., Ramaswamy K.Dudeja P. K., Am. J. Physiol.-Gastroint. Liver Physiol., 283, 626 - 633 (2002), "Modulation of Cl-/OH-Exchange Activity in Caco-2 Cells by Nitric Oxide"
  • 62. Zaragoza C., Soria E., Lopez E., Browning D., Balbin M., Lopez-Otin C.Lamas S., Mol. Pharmacol., 62, 927 - 935 (2002), "Activation of the Mitogen Activated Protein Kinase Extracellular Signal-regulated Kinase 1 and 2 by the Nitric Oxide-cGMP-cGMP-dependent Protein Kinase Axis Regulates the Expression of Matrix Metalloproteinase 13 in Vascular Endothelial Cells"
  • 63. Kawai F.Sterling P., Visual Neurosci., 19, 373 - 380 (2002), "cGMP Modulates Spike Responses of Retinal Ganglion Cells via a cGMP-gated Current"
  • 64. Tegeder I., Schmidtko A., Niederberger E., Ruth P.Geisslinger G., Neurosci. Lett. 146 - 150 & Abstract of the 13th Protein Kinase Symposium Oslo/Norway September 12th - 15th p. 31, 332, 146 - 150 (2002), "Dual Effects of Spinally Delivered 8-Bromo-cyclic Guanosine Monophosphate (8-Bromo-cGMP) in Formalin-induced Nociception in Rats"
  • 65. D'Ascenzo M., Martinotti G., Azzena G. B.Grassi G., J. Neurosci., 22, 7485 - 7492 (2002), "cGMP/Protein Kinase G-dependent Inhibition of N-Type Ca2+ Channels Induced by Nitric Oxide in Human Neuroblastoma IMR32 Cells"
  • 66. Deng W.Baker D. A., Mol. Microbiol., 44, 1141 - 1151 (2002), "A Novel Cyclic GMP-dependent Protein Kinase is Expressed in the Ring Stage of the Plasmodium Falciparum Life Cycle"
  • 67. Taylor M. K., Ahmed R., Begley M.Uhler M. D., J. Biol. Chem., 277, 37242 - 37253 (2002), "Autoinhibition and Isoform-specific Dominant Negative Inhibition of the Type II cGMP-dependent Protein Kinase"
  • 68. Saavedra A. P., Tsygankova O. M., Prendergast G. V., Dworet J. H., Cheng G.Meinkoth J. L., Oncogene, 21, 778 - 788 (2002), "Role of cAMP, PKA and Rap 1A in Thyroid Follicular Cell Survival"
  • 69. Middendorff R., Müller D., Mewe M., Mukhopadhyay A. K., Holstein A. F.Davidoff M. S., J. Clin. Endocrinol. Metab., 87, 3486 - 3499 (2002), "The Tunika Albuginea of the Human Testis is Characterized by Complex Contraction and Relaxation Activities Regulated by Cyclic GMP"
  • 70. Kaupp U. B.Seifert R., Physiol. Rev., 82, 769 - 824 (2002), "Cyclic Nucleotide-Gated Ion Channels"
  • 71. Rodriguez-Collazo P., Snyder S. K., Chiffer R. C., Zlatanova J., Leuba S. H.Smith C. L., Exp. Cell Res., 3, 1 - 10 (2002), "cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines"
  • 72. Sando O. A., Ito M.Begum N., J. Appl. Physiol., 91, 1475 - 1482 (2001), "Signal Transduction in Smooth Muscle - Selected Contribution: Insulin Utilizes NO/cGMP Pathway to Activate Myosin Phosphatase via Rho Inhibition in Vascular Smooth Muscle"
  • 73. Fujimoto S., Asano T., Sakai M., Sakurai K., Takagi D., Yoshimoto N.Itoh T., Eur. J. Pharmacol., 412, 291 - 300 (2001), "Mechanisms of Hydrogen Peroxide-induced Relaxation in Rabbit Mesenteric Small Artery"
  • 74. Cummings J. J.Wang H., Am. J. Physiol.-Lung Cell. Mol. Physiol., 280, 923 - 929 (2001), "Nitric Oxide Decreases Lung Liquid Production via Guanosine 3',5'-cyclic Monophosphate"
  • 75. Hein T. W., Wang W., Zoghi B., Muthuchamy M.Kuo L., J. Mol. Cell. Cardiol., 33, 271 - 282 (2001), "Functional and Molecular Characterization of Receptor Subtypes Mediating Coronary Microvascular Dilation to Adenosine"
  • 76. Revelli A., Costamagna C., Moffa F., Aldieri E., Ochetti S., Bosia A., Massobrio M., Lindblom B.Ghigo D., Biol. Reprod., 64, 1708 - 1712 (2001), "Signaling Pathway of Nitric Oxide-induced Acrosome Reaction in Human Spermatozoa"
  • 77. Carvajal J. A., Aguan K., Thompson L. P., Buhimschi I. A.Weiner C. P., J. Pharmacol. Exp. Ther., 297, 181 - 188 (2001), "Natriuretic Peptide-induced Relaxation of Myometrium from the Pregnant Guinea Pig is not Mediated by Guanylate Cyclase Activation"
  • 78. Hirsch J. R., Weber G., Kleta I.Schlatter E., Cell. Physiol. Biochem., 11, 77 - 82 (2001), "cGMP Serves as an Extracellular Regulator of a Ca2+-dependent K+ Channel in Immortalized Human Proximal Tubule Cells"
  • 79. Boadu E., Vaskinn S., Sundkvist E., Jaeger R.Sager G., Biochem. Pharmacol., 62, 425 - 429 (2001), "Inhibition by Guanosine Cyclic Monophosphate (cGMP) Analogues of Uptake of [H-3]3', 5'-cGMP without Stimulation of ATPase Activity in Human Erythrocyte Inside-out Vesicles"
  • 80. Pawliczak R., Cowan M. J., Huang X. L., Nanavaty U. B., Alsaaty S., Logun C.Shelhamer J. H., J. Biol. Chem., 276, 44613 - 44621 (2001), "p11 Expression in Human Bronchial Epithelial Cells is Increased by Nitric Oxide in a cGMP-dependent Pathway Involving Protein Kinase G Activation"
  • 81. Jin X. H., Siragy H. M.Carey R. M., Hypertension, 38, 309 - 316 (2001), "Renal Interstitial cGMP Mediates Natriuresis by Direct Tubule Mechanism"
  • 82. Lawrence D. W.Pryzwansky K. B., J. Immunol., 166, 5550 - 5556 (2001), "The Vasodilator-stimulated Phosphoprotein is Regulated by Cyclic GMP-dependent Protein Kinase During Neutrophil Spreading"
  • 83. Hou L. F.Wang X., J. Neurosci. Res., 66, 592 - 600 (2001), "PKC and PKA, but not PKG Mediate LPS-induced CGRP Release and [Ca2+](i) Elevation in DRG Neurons of Neonatal Rats"
  • 84. Truss M. C., Stief C. G., Jonas U., Ückert S., Becker A. J.Forssmann W.-G., Deutsche Offenlegungsschrift, 0, 0 - 0 (2001), "Verwendung von Substanzen, die den intrazellulären Gehalt von zyklischem Adenosinmonophosphat (cAMP) erhöhen oder die Aktivität cAMP-bindender Proteine stimulieren, zur Behandlung von Erkrankungen der Harnblase"
  • 85. Takeuchi T., Sugimoto K., Morimoto H., Fujita A.Hata F., Jpn. J. Pharmacol., 86, 390 - 398 (2001), "Mechanism of a Nitric Oxide Donor NOR 1-induced Relaxation in Longitudinal Muscle of Rat Proximal Colon"
  • 86. Saparov S. M., Kozono D., Rothe U., Agre P.Pohl P., J. Biol. Chem., 276, 31515 - 31520 (2001), "Water and Ion Permeation of Aquaporin-1 in Planar Lipid Bilayers"
  • 87. Hirooka K., Kourennyi D. E.Barnes S., J. Neurophysiol., 83, 198 - 206 (2000), "Calcium Channel Activation Facilitated by Nitric Oxide in Retinal Ganglion Cells"
  • 88. Yoshioka A., Yamaya Y., Saiki S., Kanemoto M., Hirose G.Pleasure D., J. Neurochem., 74, 633 - 640 (2000), "Cyclic GMP/Cyclic GMP-Dependent Protein Kinase System Prevents Excitotoxicity in an Immortalized Oligodendroglial Cell Line"
  • 89. Gertzberg N., Clements R., Jaspers I., Ferro T. J., Neumann P., Flescher E.Johnson A., Am. J. Respir. Cell. Mol. Biol., 22, 105 - 115 (2000), "Tumor Necrosis Factor-Alpha Induced Activating Protein-1 Activity is modulated by Nitric Oxide-Mediated Protein Kinase G Activation"
  • 90. Potter C. L.Hanson P. J., Gut, 46, 156 - 162 (2000), "Exogenous Nitric Oxide Inhibits Apoptosis in Guinea Pig Gastric Mucous Cells"
  • 91. Schwede F., Brustugun O. T., Zorn-Kruppa M., Doeskeland S. O.Jastorff B., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000), "Membrane-permeant, Bioactivatable Analogues of cGMP as Inducers of Cell Death in IPC-81 Leukemia Cells"
  • 92. Teoh H.Man R. Y. K., Br. J. Pharmacol., 129, 1739 - 1747 (2000), "Enhanced Relaxation of Porcine Coronary Arteries after Acute Exposure to a Physiological Level of 17 Beta-Estradiol Involves Non-Genomic Mechanisms and the Cyclic AMP Cascade"
  • 93. He P., Zeng M.Curry F. E., Am. J. Physiol.-Heart Circul. Physiol., 278, 1124 - 1133 (2000), "Dominant Role of cAMP in Regulation of Microvessel Permeability"
  • 94. Dhanakoti S. N., Gao Y. S., Nguyen M. Q.Raj J. U., J. Appl. Physiol., 88, 1637 - 1642 (2000), "Involvement of cGMP-Dependent Protein Kinase in the Relaxation of Ovine Pulmonary Arteries to cGMP and cAMP"
  • 95. Fukai T., Siegfried M. R., Ushio-Fukai M., Cheng Y., Kojda G.Harrison D. G., J. Clin. Invest., 105, 1631 - 1639 (2000), "Regulation of the Vascular Extracellular Superoxide Dismutase by Nitric Oxide and Exercise Training"
  • 96. Wang A., Martin J. A., Lembke L. A.Midura R. J., J. Biol. Chem., 275, 11082 - 11091 (2000), "Reversible Suppression of In Vitro Biomineralization by Activation of Protein Kinase A"
  • 97. Hagen V., Bendig J., Frings B., Wiesner B.Kaupp U. B., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "Novel Coumarinylmethyl-Caged Cyclic Nucleotides: Photochemistry and Application to Cyclic Nucleotide-Gated Channels"
  • 98. Wegener J. W., Feil R., Werner C., Hofmann F.Nawrath H., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "Involvement of Protein Kinase G in Mediating the Negative Inotropic Action of Cyclic GMP in the Murine Myocardium"
  • 99. Velardez M. O., De Laurentiis A., Diaz M. D., Lasaga M., Pisera D., Seilicovich A.Duvilanski B. H., Eur. J. Endocrinol., 143, 279 - 284 (2000), "Role of Phosphodiesterase and Protein Kinase G on Nitric Oxide-Induced Inhibition of Prolactin Release from the Rat Anterior Pituitary"
  • 100. Pham N., Cheglakov I., Koch C. A., de Hoog C. L., Moran M. F.Rotin D., Curr. Biol., 10, 555 - 558 (2000), "The Guanine Nucleotide Exchange Factor CNrasGEF Activates Ras in Response to cAMP and cGMP"
  • 101. Kalra D., Baumgarten G., Dibbs Z., Seta Y., Sivasubramanian N.Mann D. L., Circulation, 102, 1302 - 1307 (2000), "Nitric Oxide Provokes Tumor Necrosis Factor-Alpha Expression in Adult Feline Myocardium through a cGMP-Dependent Pathway"
  • 102. Matsunobu T.Schacht J., J. Comp. Neurol., 423, 452 - 461 (2000), "Nitric Oxide/Cyclic GMP Pathway Attenuates ATP-Evoked Intracellular Calcium Increase in Supporting Cells of the Guinea Pig Cochlea"
  • 103. Schwede F., Maronde E., Genieser H.-G.Jastorff B., Pharmacol. Ther., 87, 199 - 226 (2000), "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs"
  • 104. Zima A., Martynyuk A. E., Seubert C. N., Morey T. E., Sumners C., Cucchiara R. F.Dennis D. M., J. Mol. Cell. Cardiol., 32, 1609 - 1619 (2000), "Antagonism of the Positive Dromotropic Effect of Isoproterenol by Adenosine: Role of Nitric Oxide, cGMP-Dependent cAMP-Phosphodiesterase and Protein Kinase G"
  • 105. Musialek P., Rigg L., Terrar D. A., Paterson D. J.Casadei B., J. Mol. Cell. Cardiol., 32, 1831 - 1840 (2000), "Role of cGMP-inhibited Phosphodiesterase and Sarcoplasmic Calcium in Mediating the Increase in Basal Heart Rate with Nitric Oxide Donors"
  • 106. Lee J. J.Parsons M. E., J. Pharmacol. Exp. Ther., 295, 607 - 613 (2000), "Signaling Mechanisms Coupled to Presynaptic A(1)- and H-3-Receptors in the Inhibition of Cholinergic Contractile Responses of the Guinea Pig Ileum"
  • 107. Li J., Yang S.Billiar T. R., J. Biol. Chem., 275, 13026 - 13034 (2000), "Cyclic Nucleotides Suppress Tumor Necrosis Factor Alpha-Mediated Apoptosis by Inhibiting Caspase Activation and Cytochrome c Release in Primary Hepatocytes via a Mechanism Independent of Akt Activation"
  • 108. Gorczyca W. A., Methods Enzymol., 315, 689 - 707 (2000), "Use of Nucleoside alpha-Phosphorothioates in Studies of Photoreceptor Guanylyl Cyclase: Purification of Guanylyl Cyclase Activating Proteins"
  • 109. Palmer A. M., Messerli M. A.Robinson K. R., J. Neurobiol., 45, 30 - 38 (2000), "Neuronal Galvanotropism is Independent of External Ca2+ Entry or Internal Ca2+ Gradients"
  • 110. Ellis D. Z., Nathanson J. A.Sweadner K. J., Am. J. Physiol.-Cell Physiol., 279, 1685 - 1693 (2000), "Carbachol Inhibits Na+-K+-ATPase Activity in Choroid Plexus via Stimulation of the NO/cGMP Pathway"
  • 111. Klein G., Drexler H.Schröder F., Cardiovasc. Res., 48, 367 - 374 (2000), "Protein Kinase G Reverses all Isoproterenol Induced Changes of Cardiac Single L-Type Calcium Channel Gating"
  • 112. Hardy T. A.Brock J. A., Naunyn-Schmied. Arch. Pharmacol., 362, 559 - 567 (2000), "Effects of Agents that Modulate Intracellular cAMP Levels on Excitatory Junction Potentials Recorded in the Guinea-Pig Vas Deferens In Vitro"
  • 113. Lei S., Jackson M. F., Jia Z., Roder J., Bai D., Orser B. A.MacDonald J. F., Nature Neurosci., 3, 559 - 565 (2000), "Cyclic GMP-dependent Feedback Inhibition of AMPA Receptors is Independent of PKG"
  • 114. Brown R. L., Haley T. L.Snow S. D., Biochemistry, 39, 432 - 441 (2000), "Irreversible Activation of Cyclic Nucleotide-Gated Ion Channels by Sulfhydryl-Reactive Derivatives of Cyclic GMP"
  • 115. Taylor M. K.Uhler M. D., J. Biol. Chem., 275, 28053 - 28062 (2000), "The Amino-terminal Cyclic Nucleotide Binding Site of the Type II cGMP-dependent Protein Kinase is Essential for Full cyclic Nucleotide-dependent Activation"
  • 116. Ohyama T., Hackos D. H., Frings S., Hagen V., Kaupp U. B.Korenbrot J. I., J. Gen. Physiol., 116, 735 - 753 (2000), "Fraction of the Dark Current Carried by Ca2+ through cGMP-gated Ion Channels of Intact Rod and Cone Photoreceptors"
  • 117. Jedlitschky G., Burchell B.Keppler D., J. Biol. Chem., 275, 30069 - 30074 (2000), "The Multidrug Resistance Protein 5 Functions as an ATP-dependent Export Pump for Cyclic Nucleotides"
  • 118. Bouley R., Breton S., Sun T.-X., McLaughlin M., Nsumu N. N., Lin H. Y., Ausiello D. A.Brown D., J. Clin. Invest., 106, 1115 - 1126 (2000), "Nitric Oxide and Atrial Natriuretic Factor Stimulate cGMP-dependent Membrane Insertion of Aquaporin 2 in Renal Epithelial Cells"
  • 119. Sequeira S. M., Carvalho A. P.Carvalho C. M., Neurosci. Lett., 261, 29 - 32 (1999), "Both Protein Kinase G Dependent and Independent Mechanisms are Involved in the Modulation of Glutamate Release by Nitric Oxide in Rat Hippocampal Nerve Terminals"
  • 120. Prasad R. K., Behrooz A.Ismail-Beigi F., Eur. J. Pharmacol., 366, 101 - 109 (1999), "LY-83583 Stimulates Glucose Transporter-1-Mediated Glucose Transport Independent of Changes in cGMP Levels"
  • 121. Nawy S., J. Neurosci., 19, 2938 - 2944 (1999), "The Metabotropic Receptor mGluR6 may Signal through G(o), but not Phosphodiesterase, in Retinal Bipolar Cells"
  • 122. Yawo H., J. Neurosci., 19, 5293 - 5300 (1999), "Involvement of cGMP-Dependent Protein Kinase in Adrenergic Potentiation of Transmitter Release from the Calyx-Type Presynaptic Terminal"
  • 123. Idriss S. D., Gudi T., Casteel D. E., Kharitonov V. G., Pilz R. B.Boss G. R., J. Biol. Chem., 274, 9489 - 9493 (1999), "Nitric Oxide Regulation of Gene Transcription via Soluble Guanylate Cyclase and Type I cGMP-Dependent Protein Kinase"
  • 124. Galisteo M., Marc N., Fautrel A., Guillouzo A., Corcos L.Lagadic-Gossmann D., J. Pharmacol. Exp. Ther., 290, 1270 - 1277 (1999), "Involvement of Cyclic Nucleotide- and Calcium-Regulated Pathways in Phenobarbital-Induced Cytochrome P-450 3A Expression in Mouse Primary Hepatocytes"
  • 125. Fernandez-Tome P., Lizasoain I., Leza J. C., Lorenzo P.Moro M. A., Neuropharmacology, 38, 1307 - 1315 (1999), "Neuroprotective Effects of DETA-NONOate, a Nitric Oxide Donor, on Hydrogen Peroxide-Induced Neurotoxicity in Cortical Neurones"
  • 126. Gao Y. S., Dhanakoti S., Tolsa J. F.Raj J. U., J. Appl. Physiol., 87, 993 - 998 (1999), "Role of Protein Kinase G in Nitric Oxide- and cGMP-Induced Relaxation of Newborn Ovine Pulmonary Veins"
  • 127. Hoenderop J. G. J., Vaandrager A. B., Dijkink L., Smolenski A., Gambaryan S., Lohmann S. M., De Jonge H. R., Willems P. H. G. M.Bindels R. J. M., Proc. Natl. Acad. Sci., 96, 6084 - 6089 (1999), "Atrial Natriuretic Peptide-Stimulated Ca2+ Reabsorption in Rabbit Kidney Requires Membrane-Targeted, cGMP-Dependent Protein Kinase Type II"
  • 128. Gray D. B., Polo-Parada L., Pilar G. R., Eang P., Metzger R. R., Klann E.Meriney S. D., J. Neurochem., 72, 1981 - 1990 (1999), "A Nitric Oxide/Cyclic GMP-Dependent Protein Kinase Pathway Alters Transmitter Release and Inhibition by Somatostatin at a Site Downstream of Calcium Entry"
  • 129. Chi O. Z., Liu X.Weiss H. R., Microvasc. Res., 58, 35 - 40 (1999), "Effects of Cyclic GMP on Microvascular Permeability of the Cerebral Cortex"
  • 130. Ishida A., Sasaguri T., Miwa Y., Kosaka C., Taba Y.Abumiya T., Mol. Pharmacol., 56, 938 - 946 (1999), "Tumor Suppressor p53 but not cGMP Mediates NO-Induced Expression of p21 (Waf1/Cip1/Sdi1) in Vascular Smooth Muscle Cells"
  • 131. Jin X. C.Wu W. H., Plant Cell Physiol., 40, 1127 - 1133 (1999), "Involvement of Cyclic AMP in ABA- and Ca2+-Mediated Signal Transduction of Stomatal Regulation in Vicia faba"
  • 132. Xu R. W., Roh S. G., Loneragan K., Pullar M.Chen C., J. Physiol. - London, 520, 697 - 707 (1999), "Human GHRH Reduces Voltage-Gated K+ Currents via a non-cAMP-Dependent but PKC- Mediated Pathway in Human GH Adenoma Cells"
  • 133. Edwards E.Paton J. F. R., Am. J. Physiol. - Heart Circul. Physiol., 277, 1914 - 1923 (1999), "5-HT4 Receptors in Nucleus Tractus Solitarii Attenuate Cardiopulmonary Reflex in Anesthetized Rats"
  • 134. Komalavilas P., Shah P. K., Jo H. J.Lincoln T. M., J. Biol. Chem., 274, 34301 - 34309 (1999), "Activation of Mitogen-Activated Protein Kinase Pathways by Cyclic GMP and Cyclic GMP-Dependent Protein Kinase in Contractile Vascular Smooth Muscle Cells"
  • 135. Wiesner B.Hagen V., J. Photochem. Photobiol. B- Biol., 49, 112 - 119 (1999), "Measurement of Intracellular Ca2+ Changes Using Novel Caged Cyclic Nucleotides and Confocal Laser Scanning Microscopy"
  • 136. Hillinger S., Schmid R. A., Sandera P., Stammberger U., Schneiter D., Schoedon G.Weder W., Ann. Thorac. Surg., 68, 1138 - 1143 (1999), "8-Br-cGMP is Superior to Prostaglandin E1 for Lung Preservation"
  • 137. Lu Y.-F., Kandel E. R.Hawkins R. D., J. Neurosci., 19, 10250 - 10261 (1999), "Nitric Oxide Signaling Contributes to Late-Phase LTP and CREB Phosphorylation in the Hippocampus"
  • 138. Ropero A. B., Fuentes E., Rovira J. M., Ripoll C., Soria B.Nadal A., J. Physiol., 521, 397 - 407 (1999), "Non-Genomic Actions of 17Beta-Oestradiol in Mouse Pancreatic Beta-Cells are Mediated by a cGMP-Dependent Protein Kinase"
  • 139. Collins S. P.Uhler M. D., J. Biol. Chem., 274, 8391 - 8404 (1999), "Cyclic AMP- and Cyclic GMP-Dependent Protein Kinases Differ in Their Regulation of Cyclic AMP Response Element-Dependent Gene Transcription"
  • 140. Francis S. H.Corbin J. D., Crit. Rev. Clin. Lab. Sci., 36, 275 - 328 (1999), "Cyclic Nucleotide-Dependent Protein Kinases: Intracellular Receptors for cAMP and cGMP Action"
  • 141. Pfeifer A., Ruth P., Dostmann W., Sausbier M., Klatt P.Hofmann F., in Rev. Physiol. Biochem. Pharmacol. Berlin / Springer, 135, 105 - 149 (1999), "Structure and Function of cGMP-Dependent Protein Kinases"
  • 142. Hagen V., Bendig J., Frings S., Wiesner B., Schade B., Helm S., Lorenz D.Kaupp U. B., J. Photochem. Photobiol. B-Biol., 53, 91 - 102 (1999), "Synthesis, Photochemistry and Application of (7-Methoxycoumarin-4-yl)Methyl-Caged 8-Bromoadenosine Cyclic 3', 5'-Monophosphate and 8-Bromoguanosine Cyclic 3', 5'-Monophosphate Photolyzed in the Nanosecond Time Region"
  • 143. Hirsch J. R., Weber G., Kleta I.Schlatter E., J. Physiol., 519, 645 - 655 (1999), "A Novel cGMP-regulated K+Channel in Immortalized Human Kidney Epithelial Cells (IHKE-1)"
  • 144. Hirsch J. R., Meyer M., Mägert H.-J., Forssmann W.-G., Mollerup S., Herter P., Weber G., Cermak R., Ankorina-Stark I., Schlatter E.Kruhoffer M., J. Am. Soc. Nephrol., 10, 472 - 480 (1999), "cGMP-dependent and -independent Inhibition of a K+ Conductance by Natriuretic Peptides: Molecular and Functional Studies in Human Proximal Tubule Cells"
  • 145. Suwastika I. N.Gehring C. A., Archives of Biochemistry and Biophysics, 367, 137 - 139 (1999), "The plasma membrane H+ ATPase from Tradescantia Stem and leaf tissue is modulated in vitro by cGMP"
  • 146. Taylor M. S., McMahon A. M., Gardner J. D.Benoit J. N., Pathophysiology, 5, 233 - 245 (1999), "Cyclic nucleotides and vasoconstrictor function: physiological and pathophysiological considerations"
  • 147. Wei J.-Y., Cohen E. D., Genieser H.-G.Barnstable C. J., J. Mol. Neurosci., 10, 53 - 64 (1998), "Substituted cGMP Analogs Can Act as Selective Agonists of the Rod Photoreceptor cGMP-Gated Cation Channel"
  • 148. Kurtz A., Götz K.-H., Hamann M., Kieninger M.Wagner C., Amer. J. Physiol., 43, 709 - 717 (1998), "Stimulation of Renin Secretion by NO Donors is Related to the cAMP Pathway"
  • 149. Smolenski A., Burkhardt A. M., Eigenthaler M., Butt E., Gambaryan S., Lohmann S. M.Walter U., Naunyn-Schmied. Arch. Pharmacol., 358, 134 - 139 (1998), "Functional Analysis of cGMP-dependent Protein Kinases I and II as Mediators of NO/cGMP Effects"
  • 150. Begum N., Ragolia L., Rienzie J., McCarthy M.Duddy N., J. Biol. Chem., 273, 25164 - 25170 (1998), "Regulation of Mitogen-activated Protein Kinase Phosphatase-1 Induction by Insulin in Vascular Smooth Muscle Cells"
  • 151. Ruiz-Velasco V., Zhong J., Hume J. R.Keef K. D., Circ. Res., 82, 557 - 565 (1998), "Modulation of Ca2+ Channels by Cyclic Nucleotide Cross Activation of Opposing Protein Kinases in Rabbit Portal Vein"
  • 152. Wyatt T. A., Spurzem J. R., May K.Sisson J. H., Amer. J. Physiol.- Lung Cell Mol. Physiol., 19, 827 - 835 (1998), "Regulation of Ciliary Beat Frequency by both PKA and PKG in Bovine Airway Epithelial Cells"
  • 153. Saijonmaa O.Fyhrquist F., Cardiovasc. Res., 40, 206 - 210 (1998), "Upregulation of Angiotensin Converting Enzyme by Atrial Natriuretic Peptide and Cyclic GMP in Human Endothelial Cells"
  • 154. Maeda T., Murase N., Subbotin V., Sakamoto T., Yamada T., Terakura M.Todo S., Transplantation, 66, 844 - 851 (1998), "Analogs of Cyclic Nucleotides in Rat Liver Preservation"
  • 155. Firestein B. L.Bredt D. S., J. Neurochem., 71, 1846 - 1853 (1998), "Regulation of Sensory Neuron Precursor Proliferation by Cyclic GMP-Dependent Protein Kinase"
  • 156. Bradley K. K., Buxton I. L. O., Barber J. E., McGaw T.Bradley M. E., Amer. J. Physiol. -Cell Physiol., 44, 1668 - 1673 (1998), "Nitric Oxide Relaxes Human Myometrium by a cGMP-Independent Mechanism"
  • 157. Hagen V., Dzeja C., Bendig J., Baeger I.Kaupp U. B., J. Photochem. Photobiol., 42, 71 - 78 (1998), "Novel Caged Compounds of Hydrolysis-resistant 8-Br-cAMP and 8-Br-cGMP: Photolabile NPE Esters"
  • 158. Suhasini M., Li H. E., Lohmann S. M., Boss G. R.Pilz R. B., Mol. Cell. Biol., 18, 6983 - 6994 (1998), "Cyclic-GMP-Dependent Protein Kinase Inhibits the Ras/Mitogen-Activated Protein Kinase Pathway"
  • 159. Wexler E. M., Stanton P. K.Nawy S., J. Neurosci., 18, 2342 - 2349 (1998), "Nitric Oxide Depresses GABA(A) Receptor Function Via Coactivation of cGMP-Dependent Kinase and Phosphodiesterase"
  • 160. Han J., Kim E., Lee S. H., Yoo S., Ho W.-K.Earm Y. E., Pflugers Arch.-Eur. J. Physiol., 435, 388 - 393 (1998), "cGMP Facilitates Calcium Current via cGMP-Dependent Protein Kinase in Isolated Rabbit Ventricular Myocytes"
  • 161. He P., Zeng M.Curry F. E., Amer. J. Physiol.-Heart Circ. Phy., 43, 1865 - 1874 (1998), "CGMP Modulates Basal and Activated Microvessel Permeability Independently of [CA2+](1)"
  • 162. Vallina J. R. P., Antolin L. M., Cantabrana B., Sanchez M.Hidalgo A., Gen. Pharmacol., 30, 25 - 29 (1998), "Nitric Oxide and Cyclic Nucleotides Participate in the Relaxation of Diclofenac on Rat Uterine Smooth Muscle"
  • 163. Mancini L., Moradi-Bidhendi N., Brandi M. L.MacIntyre I., Biochem. Biophys. Res. Commun., 243, 785 - 790 (1998), "Nitric Oxide Superoxide and Peroxynitrite Modulate Osteoclast Activity"
  • 164. Uneyama C., Uneyama H., Akaike N.Williamson J., Eur. J. Pharmacol., 347, 355 - 361 (1998), "Cyclic GMP Inhibits Cytoplasmic CA2+ Oscillation by Increasing Ca2+-ATPase Activity in Rat Megacaryocytes"
  • 165. Hardy P., Abran D., Hou X., Lahaie I., Peri K. G., Asselin P., Varma D. R.Chemtob S., Circ. Res., 83, 721 - 729 (1998), "A Major Role for Prostacyclin in Nitric Oxide-Induced Ocular Vasorelaxation in the Piglet"
  • 166. Hebert M. C., Schwede F., Jastorff B.Cote R. H., J. Biol. Chem., 273, 5557 - 5565 (1998), "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs"
  • 167. Alioua A., Tanaka Y., Wallner M., Hofmann F., Ruth P., Meera P.Toro L., J. Biol. Chem., 273, 32950 - 32956 (1998), "The Large Conductance, Voltage-Dependent, and Calcium-Sensitive K+ Channel, Hslo, is a Target of cGMP-Dependent Protein Kinase Phosphorylation In Vivo"
  • 168. Vaandrager A. B., Bot A. G. M.De Jonge H. R., Gastroenterology, 112, 437 - 443 (1997), "Guanosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase II Mediates Heat-Stable Enterotoxin-Provoked Chloride Secretion in Rat Intestine"
  • 169. Hölschermann H., Noll T., Hempel A.Piper H. M., Amer. J. Physiol.-Heart Circul. Physiol., 41, 91 - 98 (1997), "Dual Role of cGMP in Modulation of Macromolecule Permeability of Aortic Endothelial Cells"
  • 170. Kumar R., Namiki T.Joyner R. W., Cardiovasc. Res., 33, 573 - 582 (1997), "Effects of cGMP on L-Type Calcium Current of Adult and Newborn Rabbit Ventricular Cells"
  • 171. Bonkale W. L., Cowburn R. F., Winblad B.Fastbom J., Brain Res., 763, 1 - 13 (1997), "Autoradiographic Characterization of (H-3)cGMP Binding Sites in the Rat Brain."
  • 172. Perez-Vallina J. R., Revuelta M. P., Cantabrana B.Hidalgo A., Life Sci., 61, 869 - 880 (1997), "Effect of RP Diastereoisomer of Adenosine 3', 5' Cyclic-Monophosphothioate on the cAMP-Dependent Relaxation of Smooth Muscle."
  • 173. Yamamoto K., Ikeda U.Shimada K., J. Mol. Cell Cardiol., 29, 2375 - 2382 (1997), "Natriuretic Peptides Modulate Nitric Oxide Synthesis in Cytokine-stimulated Cardiac Myocytes"
  • 174. Lemos V. S., Bucher B., Cortes S. F.Takeda K., Eur. J. Neurosci., 9, 1144 - 1152 (1997), "Inhibition of [Ca2+]i Transients in Rat Adrenal Chromaffin Cells by Neuropeptide Y: Role for a cGMP-dependent Protein Kinase-activated K+ Conductance"
  • 175. Takeuchi T., Fujita A., Nishio H.Hata F., J. Smooth Muscle Res., 33, 163 - 174 (1997), "Essential Role of Newly Synthesized ATP for Cyclic GMP-induced Relaxation in Alpha-Toxin Permeabilized Smooth Muscle of Rat Proximal Colon"
  • 176. Dixon D. B.Copenhagen D. R., J. Neurosci., 17, 8945 - 8954 (1997), "Metabotropic Glutamate Receptor-Mediated Suppression of an Inward Rectifier Current is Linked via a cGMP Cascade"
  • 177. Soff G. A., Cornwell T. L., Cundiff D. L., Gately S.Lincoln T. M., J. Clin. Invest., 100, 2580 - 2587 (1997), "Smooth Muscle Cell Expression of Type I Cyclic GMP-Dependent Protein Kinase is Suppressed by Continuous Exposure to Nitrovasodilators, Theophylline, Cyclic GMP, and Cyclic AMP"
  • 178. Selbach O., Brown R. E.Haas H. L., Neuropharmacol., 36, 1539 - 1548 (1997), "Long-Term Increase of Hippocampal Exitability By Histamine and Cyclic AMP"
  • 179. Syrovets T., Tippler B., Rieks M.Simmet T., Blood, 89, 4574 - 4583 (1997), "Plasmin is a Potent and Specific Chemoattractant for Human Peripheral Monocytes Acting via a Cyclic Guanosine Monophosphate-Dependent Pathway"
  • 180. Ingram S. L.Williams J. T., J. Physiol., 492, 97 - 106 (1996), "Modulation of the Hyperpolarization-activated Current (Ih) by Cyclic Nucleotides in Guinea-pig Primary Afferent Neurons"
  • 181. Nakamura A., Fujita M.Shiomi H., Brit. J. Pharmacol., 117, 407 - 412 (1996), "Involvement of Endogenous Nitric Oxide in the Mechanism of Bradykinin-induced Peripheral Hyperalgesia"
  • 182. Jackson W. F., Pharmacology, 52, 226 - 234 (1996), "Rp Diastereomeric Analogs of cAMP Inhibit Both cAMP-and cGMP-Induced Dilation of Hamster Mesenteric Small Arteries"
  • 183. Peng W., Hoidal J. R.Farrukh I. S., J. Appl. Physiol., 81, 1264 - 1272 (1996), "Regulation of Ca2+-Activated K+Channels in Pulmonary Vascular Smooth Muscle Cells: Role of Nitric Oxide"
  • 184. Hichami A., Boichot E., Germain N., Coqueret O.Lagente V., Life Sci., 59, 255 - 261 (1996), "Interactions Between cAMP- and cGMP-dependent Protein Kinase Inhibitors and Phosphodiesterase IV Inhibitors on Arachidonate Release from Human Monocytes"
  • 185. Barger S. W.Mattson M. P., Mol. Brain Res., 40, 116 - 126 (1996), "Induction of Neuroprotective kB-dependent Transcription by Secreted Forms of the Alzheimer's Beta-Amyloid Precursor"
  • 186. Wilderman M. J.Armstead W. M., Am. J. Physiol., 39, 869 - 874 (1996), "Relationship Between Nitric Oxide and Opioids in Hypoxia-induced Pial Artery Vasodilation"
  • 187. Rooney T. A., Joseph S. K., Queen C.Thomas A. P., J. Biol. Chem., 271, 19817 - 19825 (1996), "Cyclic GMP Induces Oscillatory Calcium Signals in Rat Hepatocytes"
  • 188. Mathes C.Thompson S. H., J. Neurosci., 16, 1702 - 1709 (1996), "The Nitric Oxide/cGMP Pathway Couples Muscarinic Receptors to the Activation of Ca2+ Influx"
  • 189. Mothet J.-P., Fossier P., Tauc L.Baux G., Proc. Natl. Acad. Sci. USA, 93, 8721 - 8726 (1996), "Opposite Actions of Nitric Oxide on Cholinergic Synapses: Which Pathways?"
  • 190. Guihard G., Combettes L.Capiod T., Biochem. J., 318, 849 - 855 (1996), "3':5'-Cyclic Guanosine Monophosphate (cGMP) Potentiates the Inositol 1,4,5-Trisphosphate- evoked Ca2+ Release in Guinea-pig Hepatocytes"
  • 191. Jorgensen T. D., Dissing S.Gromada J., FEBS Lett., 391, 117 - 120 (1996), "Cyclic GMP Potentiates Phenylephrine but not Cyclic ADP-ribose-evoked Calcium Release from Rat Lacrimal Acinar Cells"
  • 192. Rodriguez-Pascual F., Miras-Portugal M. T.Torres M., Mol. Pharmacol., 49, 1058 - 1070 (1996), "Effect of Cyclic GMP-increasing Agents Nitric Oxide and C-type Natriuretic Peptide on Bovine Chromaffin Cell Function: Inhibitory Role Mediated by Cyclic GMP-dependent Protein Kinase"
  • 193. Wei J. Y., Cohen E. D., Yan Y.-Y., Genieser H.-G.Barnstable C. J., Biochemistry, 35, 16815 - 16823 (1996), "Identification of Competitive Antagonists of the Rod Photoreceptor cGMP-Gated Cation Channel: Beta-Phenyl-1,N(2)-Etheno-Substituted cGMP Analogues as Probes of the cGMP-Binding Site"
  • 194. Nakamura A.Shiomi H., Fol. Pharmacol. Jap., 108, 143 - 148 (1996), "Signal Transduction System Involved in the Mechanism of Peripheral Mechanical Hyperalgesia"
  • 195. Pineda J., Kogan J. H.Aghajanian G. K., J. Neurosci., 16, 1389 - 1399 (1996), "Nitric Oxide and Carbon Monoxide Activate Locus Ceruleus Neurons Through a cGMP-Dependent Protein Kinase: Involvement of a Nonselective Cationic Channel"
  • 196. Sadighi Akha A. A., Willmott N. J., Brickley K., Dolphin A. C., Galione A.Hunt S. V., J. Biol. Chem., 271, 7297 - 7300 (1996), "Anti-Ig-induced Calcium Influx in Rat B Lymphocytes Mediated by cGMP Through a Dihydropyridine-sensitive Channel"
  • 197. Holzmann A., Bloch K. D., Sanchez L. S., Filippov G.Zapol W. M., Amer. J. Physiol.- Lung Cell. Mol. Physiol., 15, 981 - 986 (1996), "Hyporesponsiveness to Inhaled Nitric Oxide in Isolated, Perfused Lungs from Endotoxin-Challenged Rats"
  • 198. Kuenzli K. A., Bradley M. E.Buxton I. L. O., Br. J. Pharmacol., 119, 737 - 743 (1996), "Cyclic GMP-independent Effects of Nitric Oxide on Guinea-pig Uterine Contractility"
  • 199. Butt E.Walter U., in 'Platelets: A Practical Approach' IRL Press Oxford, 0, 259 - 278 (1996), "Cyclic Nucleotides: Measurement and Function"
  • 200. Anciaux K., Roymans D.Slegers H., Arch. Physiol. Biochem., 104, 32 - 0 (1996), "Effect of cAMP- and cGMP-Analogues on the Enzymatic Activity of the Nucleoside Diphosphate Kinase of Rat C6 Glioma"
  • 201. Ückert S., Truss M. C., Stief C. G., Becker A. J.Jonas U., Jahrbuch der Urologie, 0, 0 - 0 (1996), "Beeinflussung des Tonuszustandes Porciner Detrusormuskulatur durch Modulation Intrazellulärer Schlüsselenzyme in Vitro"
  • 202. Schwede F., Ph.D. Thesis, 0, 0 - 0 (1996), "Synthese und Eigenschaften ausgewählter Analoga von cGMP und ihr Einsatz in der biologischen Forschung"
  • 203. Bayliss M. A., Pereira L., Games D. E., Brenton A. G., Harris F. M., Newton R. P.Walton T. J., Proc. 2. MS-Pharmaday Siena Italy #C 17-67 - 68, 0, 67 - 68 (1996), "Fast-Atom Bombardment Mass Spectrometry of Site-Specific Effectors of Cyclic Nucleotide Dependent Protein Kinases"
  • 204. Pfeifer A., Aszódi A., Seidler U., Ruth P., Hofmann F.Fässler R., Science, 274, 2082 - 2086 (1996), "Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-dependent Protein Kinase II"
  • 205. Sidhu J. S.Omiecinski C. J., J. Biol. Chem., 270, 12762 - 12773 (1995), "cAMP-associated Inhibition of Phenobarbital-inducible Cytochrome P450 Gene Expression in Primary Rat Hepatocyte Cultures"
  • 206. Andriantsitohaina R., Lagaud G. J.-L., Andre A., Muller B.Stoclet J.-C., Am. J. Physiol., 37, 1223 - 1231 (1995), "Effects of cGMP on Calcium Handling in ATP-stimulated Rat Resistance Arteries"
  • 207. Rodriguez-Pascual F., Miras-Portugal M. T.Torres M., Neuroscience, 67, 149 - 157 (1995), "Cyclic GMP-dependent Protein Kinase Activation Mediates Inhibition of Catecholamines Secretion and Ca 2+ Influx in Bovine Chromaffin Cells"
  • 208. Pöhler D., Butt E., Meißner J., Müller S., Walter U., Lohmann S. M.Jarchau T., FEBS Lett., 374, 419 - 425 (1995), "Expression, Purification, and Characterization of the cGMP-dependent Protein Kinases Iß and II Using the Baculovirus System"
  • 209. Eichholtz-Wirth H., Br. J. Cancer, 72, 287 - 292 (1995), "Reversal of Radiation-induced Cisplatin Resistance in Murine Fibrosarcoma Cells by Selective Modulation of the Cyclic GMP-dependent Transduction Pathway"
  • 210. Petritsch C., Woscholski R., Edelmann H. M. L.Ballou L. M., J. Biol. Chem., 270, 26619 - 26625 (1995), "Activation of p70 S6 Kinase and erk-encoded Mitogen-activated Protein Kinases is Resistant to High Cyclic Nucleotide Levels in Swiss 3T3 Fibroblasts"
  • 211. Lawson C. A., Smerling A. J., Naka Y., Burkhoff D., Dickstein M. L., Stern D. M.Pinsky D. J., Am. J. Physiol., 268, 2056 - 2062 (1995), "Selective Reduction of PVR by Inhalation of a cGMP Analogue in a Porcine Model of Pulmonary Hypertension"
  • 212. Scott S.-P.Tanaka J. C., Biochemistry, 34, 2338 - 2347 (1995), "Molecular Interactions of 3',5'-Cyclic Purine Analogues with the Binding Site of Retinal Rod Ion Channels"
  • 213. Frings S., Seifert R., Godde M.Kaupp U. B., Neuron, 15, 169 - 179 (1995), "Profoundly Different Calcium Permeation and Blockage Determine the Specific Function of Distinct Cyclic Nucleotide-Gated Channels"
  • 214. Wild N., Herberg F. W., Hofmann F.Dostmann W. R. G., FEBS Lett., 374, 356 - 362 (1995), "Expression of a Chimeric, cGMP-sensitive Regulatory Subunit of the cAMP-dependent Protein Kinase Type I(Alpha)"
  • 215. Ouedraogo S., Stoclet J.-C.Bucher B., Br. J. Pharmacol., 112, 867 - 872 (1994), "Effects of cyclic GMP and Analogues on Neurogenic Transmission in the Rat Tail Artery"
  • 216. Ohigashi T., Brookins J.Fisher J. W., J. Clin. Invest., 92, 1587 - 1591 (1994), "Interaction of Nitric Oxide and Cyclic Guanosine 3', 5'- Monophosphate in Erythropoietin Production"
  • 217. Zhuo M., Hu Y., Schultz C., Kandel E. R.Hawkins R. D., Nature, 368, 635 - 639 (1994), "Role of Guanylyl Cyclase and cGMP-dependent Protein Kinase in Long-term Potentiation"
  • 218. Pinsky D. J., Naka Y., Chowdhury N. C., Liao H., Oz M. C., Michler R. E., Kubaszewski E., Malinski T.Stern D. M., Proc. Natl. Acad. Sci. USA, 91, 12086 - 12090 (1994), "The Nitric Oxide Cyclic GMP Pathway in Organ Transplantation: Critical Role in Successful Lung Preservation"
  • 219. Archer S. L., Huang J. M. C., Hampl V., Nelson D. P., Schultz P. J.Weir E. K., Proc. Natl. Acad. Sci. USA, 91, 7583 - 7587 (1994), "Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-sensitive K Channel by cGMP-dependent Protein Kinase"
  • 220. Hildebrandt H., Dissertation, 0, 27 - 67 (1994), "cAMP-abhängige Proteinkinase im Antennallobus der Honigbiene: Regulation bei der Verarbeitung chemosensorischer Signale"
  • 221. Hawkins R. D., Zhuo M.Arancio O., J. Neurobiol., 27, 652 - 665 (1994), "Nitric Oxide and Carbon Monoxide as Possible Retrograde Messengers in Hippocampal Long-Term Potentiation"
  • 222. Gorczyca W. A., Van Hooser J. P.Palczewski K., Biochemistry, 33, 3217 - 3222 (1994), "Nucleotide Inhibitors and Activators of Retinal Guanylate Cyclase"
  • 223. Schuman E. M., Meffert M. K., Schulmann H.Madison D. V., Proc. Natl. Acad. Sci. USA, 91, 11958 - 11962 (1994), "An ADP-ribosyltransferase as a Potential Target for Nitric Oxide Action in Hippocampal Long-term Potentiation"
  • 224. Pilz R. B., Berjis M., Idriss S. D., Scheele J. S., Suhasini M., Gao L., Scheffler I. E.Boss G. R., J. Biol. Chem., 269, 32155 - 32161 (1994), "Isolation and Characterization of HL-60 Cells Resistant to Nitroprusside-Induced Differentiation"
  • 225. Sharma O. P., Flores J. A., Leong D. A.Veldhuis J. D., Endocrinology, 134, 1915 - 1923 (1994), "Cellular Basis for Follicle-Stimulating Hormone-Stimulated Calcium Signaling in Single Rat Sertoli Cells: Possible Dissociation from Effects of Adenosine 3',5'-Monophosphate"
  • 226. Francis S. H.Corbin J. D., Adv. Pharmacol., 26, 115 - 170 (1994), "Progress in Understanding the Mechanism and Function of Cyclic GMP-Dependent Protein Kinase"
  • 227. Bakker R., Dekker K., De Jonge H. R.Groot J. A., Am. J. Physiol., 264, 362 - 368 (1993), "VIP, Serotonin, and Epinephrine Modulate the Ion Selectivity of Tight Junctions of Goldfish Intestine"
  • 228. Butt E., Geiger J., Jarchau T., Lohmann S. M.Walter U., Neurochem. Res., 18, 27 - 42 (1993), "The cGMP-dependent Protein Kinase - Gene, Protein and Function"
  • 229. Brown R. L., Gerber W. V.Karpen J. W., Proc. Natl. Acad. Sci. USA, 90, 5369 - 5373 (1993), "Specific Labeling and Permanent Activation of the Retinal Rod cGMP-activated Channel by the Photoaffinity Analog 8-p-Azidophenacylthio-cGMP"
  • 230. Brown R. L., Bert R. J., Evans F. E.Karpen J. W., Biochemistry, 32, 10089 - 10095 (1993), "Activation of Retinal Rod cGMP-Gated Channels: What Makes for an Effective 8-Substituted Derivative of cGMP?"
  • 231. Ishizuka J., Beauchamp R. D., Townsend C. M., Greeley G. H.Thompson J. C., J. Cell. Physiol., 150, 1 - 7 (1992), "Receptor-mediated Autocrine Growth-stimulatory Effect of 5-Hydroxytryptamine on Cultured Human Pancreatic Carcinoid Cells"
  • 232. Butt E., Nolte C., Schulz S., Beltman J., Beavo J. A., Jastorff B.Walter U., Biochem. Pharmacol., 43, 2591 - 2600 (1992), "Analysis of the Functional Role of cGMP-dependent Protein Kinase in Intact Human Platelets Using a Specific Activator 8-pCPT-cGMP"
  • 233. Sekhar K. R., Hatchett R. J., Shabb J. B., Wolfe L., Francis S. H., Wells J. W., Jastorff B., Butt E., Chakinala M. M.Corbin J. D., Mol. Pharmacol., 42, 103 - 108 (1992), "Relaxation of Pig Coronary Arteries By New and Potent cGMP Analogs That Selectively Activate Type I alpha Compared to Type I beta cGMP-Dependent Protein Kinase"
  • 234. Forte L. R., Thorne P. K., Eber S. L., Krause W. J., Freeman R. H., Francis S. H.Corbin J. D., Am. J. Physiol., 263, 607 - 615 (1992), "Stimulation of Intestinal Cl- Transport by Heat-stable Enterotoxin: Activation of cAMP-dependent Protein Kinase by cGMP"
  • 235. Ruth P., Landgraf W., Keilbach A., May B., Egleme C.Hofmann F., Eur. J. Biochem., 202, 1339 - 1344 (1991), "The Activation of Expressed cGMP-dependent Protein Kinase Isozymes I alpha and I beta is Determined by the Different Amino-termini"
  • 236. Shabb J. B., Buzzeo B. D., Ng L.Corbin J. D., J. Biol. Chem., 266, 24320 - 24326 (1991), "Mutating Protein Kinase cAMP-binding Sites into cGMP-binding Sites"
  • 237. Lau K.Bourdeau J. E., J. Biol. Chem., 264, 4028 - 4032 (1989), "Evidence for cAMP-dependent Protein Kinase in Mediating the Parathyroid Hormone-stimulated Rise in Cytosolic Free Calcium in Rabbit Connecting Tubules"
  • 238. Wolfe L., Corbin J. D.Francis S. H., J. Biol. Chem., 264, 7734 - 7741 (1989), "Characterization of a Novel Isozyme of cGMP-dependent Protein Kinase From Bovine Aorta"
  • 239. Tanaka J. C., Eccleston J. F.Furman R. E., Biochemistry, 28, 2776 - 2784 (1989), "Photoreceptor Channel Activation by Nucleotide Derivatives"
  • 240. Caretta A.Saibil H., J. Cell Biol., 108, 1517 - 1522 (1989), "Visualization of Cyclic Nucleotide Binding Sites in the Vertebrate Retina by Fluorescence Microscopy"
  • 241. Erneux C.Miot F., Methods Enzymol., 159, 520 - 530 (1988), "Cyclic Nucleotide Analogs Used to Study Phosphodiesterase Catalytic and Allosteric Sites"
  • 242. Francis S. H., Noblett B. D., Todd B. W., Wells J. N.Corbin J. D., Mol. Pharmacol., 34, 506 - 517 (1988), "Relaxation of Vascular and Tracheal Smooth Muscle by Cyclic Nucleotide Analogs That Preferentially Activate Purified cGMP-Dependent Protein Kinase"
  • 243. Gillespie P. G.Baevo J. A., J. Biol. Chem., 263, 8133 - 8141 (1988), "Characterization of a Bovine Cone Photoreceptor Phosphodiesterase Purified by Cyclic GMP-Sepharose Chromatography"
  • 244. Koo G. C., Jewell M. E., Manyak C. L., Sigal N. H.Wicker L. S., J. Immunol., 140, 3249 - 3252 (1988), "Activation of Murine Natural Killer Cells and Macrophages by 8-Bromoguanosine"
  • 245. Clair T., Ally S., Tagliaferri P., Robins R. K.Cho-Chung Y. S., FEBS Lett., 224, 377 - 384 (1987), "Site-selective Cyclic AMP Analogs Induce Nuclear Translocation of the RII cAMP Receptor Protein in Ha-MuSV-Transformed NIH/3T3 Cells"
  • 246. Sugiyama K., Takada K.Yamamoto I., European Patent Application Filing date 10.08.87, 87111542, 1 - 36 (1987), "Cosmetic Agent for Application to Skin"
  • 247. Braumann T., Erneux C., Petridis G., Stohrer W.-D.Jastorff B., Biochim. Biophys. Acta, 871, 199 - 206 (1986), "Hydrolysis of Cyclic Nucleotides by a Purified cGMP- stimulated Phosphodiesterase: Structural Requirements for Hydrolysis"
  • 248. Corbin J. D., Oegreid D., Miller J. P., Suva R. H., Jastorff B.Doeskeland S. O., J. Biol. Chem., 261, 1208 - 1214 (1986), "Studies of cGMP Analog Specificity and Function of the Two Intrasubunit Binding Sites of cGMP-dependent Protein Kinase"
  • 249. Erneux C., Miot F., Van Haastert P. J. M.Jastorff B., J. Cyclic Nucleotide Protein Phosphorylation Res., 10, 463 - 472 (1985), "The Binding of Cyclic Nucleotide Analogs to a Purified Cyclic GMP- Stimulated Phosphodiesterase from Bovine Adrenal Tissue"
  • 250. Zimmerman A. L., Yamanaka G., Eckstein F., Baylor D. A.Stryer L., Proc. Natl. Acad. Sci. USA, 82, 8813 - 8817 (1985), "Interaction of Hydrolysis-resistant Analogs of Cyclic GMP with the Phosphodiesterase and Light - sensitive Channel of Retinal Rod Outer Segments"
  • 251. Kesbeke F., Baraniak J., Bulgakov R., Jastorff B., Morr M., Petridis G., Stec W. J., Seela F.Van Haastert P. J. M., Eur. J. Biochem., 151, 179 - 186 (1985), "Cyclic Nucleotide Specificity of the Activator and Catalytic Sites of a cGMP-stimulated cGMP Phosphodiesterase from Dictyostelium discoideum."
  • 252. Bruehl C. L.Berry R. W., J. Neurosci., 5, 1233 - 1238 (1985), "Regulation of Synthesis of the Neurosecretory Egg-laying Hormone of Aplysia: Antagonistic Roles of Calcium and Cyclic Adenosine 3':5'- Monophosphate"
  • 253. Beebe S. J., Holloway R., Rannels S. R.Corbin J. D., J. Biol. Chem., 259, 3539 - 3547 (1984), "Two Classes of cAMP Analogs Which Are Selective for the Two Different cAMP-binding Sites of Type II Protein Kinase Demonstrate Synergism When Added Together to Intact Adipocytes"
  • 254. Erneux C., Couchie D., Dumont J. E.Jastorff B., Adv. Cyclic Nucleotide Protein Phosphorylation Res., 16, 107 - 118 (1984), "Cyclic Nucleotide Derivatives as Probes of Phosphodiesterase Catalytic and Regulatory sites"
  • 255. Jastorff B., in: Cell Regulation by Intracellular Signal Molecules St. Swillens ed. 195 - 207 Plenum Press New York London, 0, 0 - 0 (1982), "The Effects of cyclic Nucleotide Derivatives on Cell Metabolism"
  • 256. Rapoport R. M., Draznin M. B.Murad F., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982), "Sodium Nitroprusside-induced Protein Phosphorylation in Intact Rat Aorta is Mimicked by 8-Bromo Cyclic GMP"
  • 257. Rannels S. R.Corbin J. D., J. Biol. Chem., 255, 7085 - 7088 (1980), "Two Different Intrachain cAMP Binding Sites of cAMP-Dependent Protein Kinases"
  • 258. Francis S. H., Lincoln T. M.Corbin J. D., J. Biol. Chem., 255, 620 - 626 (1980), "Characterization of a Novel cGMP Binding Protein from Rat Lung"
  • 259. Peikin S. R., Costenbader C. L.Gardner J. D., J. Biol. Chem., 254, 5321 - 5327 (1979), "Actions of Derivatives of Cyclic Nucleotides on Dispersed Acini from Guinea Pig Pancreas - Discovery of a Competitive Antagonist of the Action of Cholecystokinin"
  • 260. O'Neill J. P., Li A. P.Hsie A. W., BBA, 497, 35 - 45 (1977), "Action of Cyclic Nucleotide Analogues in Chinese Hamster Ovary Cells"
  • 261. Free C. A.Paik V. S., Endo, 100, 1287 - 1293 (1977), "Adrenal Stereoidogenic Actions of Cyclic Nucleotide Derivatives in the Rat"
  • 262. Dills W. L., Beavo J. A., Bechtel P. J., Myers K. R., Sakai L. J.Krebs E. G., Biochemistry, 15, 3724 - 3731 (1976), "Binding of Adenosine 3', 5'- Monophosphate Dependent Protein Kinase Regulatory Subunit to Immobilized Cyclic Nucleotide Derivatives"
  • 263. Kneer N. M., Bosch A. L., Clark M. G.Lardy H. A., Proc. Natl. Acad. Sci. USA, 71, 4523 - 4527 (1974), "Glucose Inhibition of Epinephrine Stimulation of Hepatic Gluconeogenesis by Blockade of the alpha-Receptor Function"
  • 264. Michal G., Mühlegger K., Nelboeck M., Thiessen C.Weimann G., Pharmacol. Res. Commun., 6, 203 - 252 (1974), "Cyclophosphates VI. Cyclophosphates as Substrates and Effectors of Phosphodiesterase"
  • 265. Kuo J. F., Miyamoto E.Reyes P. L., Biochem. Pharmacol., 23, 2011 - 2021 (1974), "Activation and Dissociation of Adenosine 3', 5'- Monophosphate-dependent and Guanosine 3', 5'- monophosphate-dependent Protein Kinases by Various Cyclic Nucleotide Analogs"
  • 266. Nelböck M., Michal G.Weimann G., Pure Appl. Chem., 35, 411 - 437 (1973), "Analogues of Cyclic AMP and their Physiological Response"
  • 267. Szaduykis-Szadurski L., Weimann G.Berti F., Pharmacol. Res. Commun., 4, 63 - 69 (1972), "Pharmacological Effects of Cyclic Nucleotides and their Derivatives on Tracheal Smooth Muscle"

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