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8-Br-7-CH-cADPR

8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose ( 8-Br-7-CH-cADPR ), sodium salt
Membrane-permeant and hydrolysis-resistant cADPR antagonist
Cat. No.: B 100
    
CAS No.: [189876-06-0]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: B 100-005
Unit: 0.5 µmol / ~310 µg
$410.00
For other salt forms please inquire. 8-Br-7-CH-cADPR is a membrane-permeant and hydrolysis-resistant antagonist of the second messenger cADPR (Cat. No. C 005). Detailed technical information available. References: Sethi et al., J. Biol. Chem., 272, 16358 - 16363 (1997); Guse et al., Nature, 398, 70 - 73 (1999).
Cat. No. B 100
CAS number [189876-06-0]
Purity > 97 % HPLC
Salt form Sodium
Storage temperature -70°C / -94°F
Molecular formula C₁₆H₂₁BrN₄O₁₃P₂ (free acid)
Molecular weight [g/mol] 619,2 (free acid)
Absorption max [nm] 277
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10850
  • 1. Guse A. H., da Silva C. P., Berg I., Skapenko A. L., Weber K., Heyer P., Hohenegger M., Ashamu G. A., Schulze-Koops H., Potter B. V.Mayr G. W., Nature, 398, 70 - 73 (1999), "Regulation of Calcium Signalling in T Lymphocytes by the Second Messenger Cyclic ADP-Ribose"
  • 2. Sethi J. K., Empson R. M., Bailey V. C., Potter B. V. L.Galione A., J. Biol. Chem., 272, 16358 - 16363 (1997), "7-Deaza-8-Bromo-Cyclic ADP-Ribose, the First Membrane-Permeant, Hydrolysis-Resistant Cyclic ADP-Ribose Antagonist"