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8-Br-7-CH-ADPR

8- Bromo- 7- deazaadenosine- 5'- O- diphosphoribose ( 8-Br-7-CH-ADPR ), sodium salt
Cat. No.: B 103
    
CAS No.: [1011457-95-6]
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Product Name Price (net) Qty
Cat. No.: B 103-005
Unit: 0.5 µmol / ~0.3 mg
$350.00

For other salt forms please inquire. Putative antagonist of the second messenger ADP-ribose (ADPR), inhibiting ADPR-activated cation transport through TRPM2. Detailed technical information available. References: Moreau et al., J. Med. Chem., 56, 10079 - 10102 (2013). Compare: Partida-Sanchez et al., J. Immunol., 179, 7827 - 7839 (2007).

Cat. No. B 103
CAS number [1011457-95-6]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₆H₂₃BrN₄O₁₄P₂ (free acid)
Molecular weight [g/mol] 637,2 (free acid)
Absorption max [nm] 277
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13250
  • 1. Partida-Sanchez S., Gasser A., Fliegert R., Siebrands C. C., Dammermann W., Shi G., Mousseau B. J., Sumoza-Toledo A., Bhagat H., Walseth T. F., Guse A. H.Lund F. E., J. Immunol., 179, 7827 - 7839 (2007), "Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction"