0 Items - $0.00
Categories
A to Z

8-Br-5'-GMP

8- Bromoguanosine- 5'- O- monophosphate ( 8-Br-5'-GMP ), sodium salt
Precursor for 8-modified 5'-GMP derivatives
Cat. No.: B 057
    
CAS No.: [21870-09-7]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: B 057-10
Unit: 10 µmol / ~4.4 mg
$86.00
For other salt forms or higher purity please inquire.
Analogue of 5'-GMP with changed syn/anti ratio for receptor mapping studies and as starting structure for 8-modified 5'-GMP derivatives. Detailed technical information available. References: Lassota et al., Z. Naturforsch., 39C, 55 - 63 (1984); Collier & Wagner, Org. Biomol. Chem., 4, 4526 - 4532 (2006).
Cat. No. B 057
CAS number [21870-09-7]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₃BrN₅O₈P (free acid)
Molecular weight [g/mol] 442,1 (free acid)
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200
  • 1. Collier A.Wagner G., Org. Biomol. Chem., 4, 4526 - 4532 (2006), "A Facile Two-Step Synthesis of 8-Arylated Guanosine Mono- and Triphosphates (8-Aryl GXPs)"
  • 2. Lassota P., Stolarski R.Shugar D., Z. Naturforsch. C, 39, 55 - 63 (1984), "Conformation about the Glycosidic Bond and Susceptibility to 5'-Nucleotidase of 8-Substituted Analogues of 5'-GMP"
  • 3. Rapoport R. M., Draznin M. B.Murad F., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982), "Sodium Nitroprusside-induced Protein Phosphorylation in Intact Rat Aorta is Mimicked by 8-Bromo Cyclic GMP"