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Alternative structural projections:

8-Br-2'-O-Me-cAMP

8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-Br-2'-O-Me-cAMP ), sodium salt
Epac agonist
Cat. No.: B 022
    
CAS No.: [612513-13-0]
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Product Name Price (net) Qty
Cat. No.: B 022-05
Unit: 5 µmol / ~2.2 mg
$177.00
For other salt forms please inquire. Specific activator of the exchange protein activated by cyclic AMP (Epac) or cAMP-GEF, respectively, while protein kinase A is not affected. Suitable for direct comparison with common 8-Br-cAMP (Cat. No. B 007), which activates both, PKA and Epac. Detailed technical information and updated reference list available. References: Christensen et al., J. Biol. Chem., 278, 35394 - 35402 (2003); Traver et al., Mol. Pharmacol., 70, 30 - 40 (2006).
Cat. No. B 022
Patent Information Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
CAS number [612513-13-0]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₁H₁₂BrN₅O₆P · Na
Molecular weight [g/mol] 444,1
Modifications 8-cAMP, 2'-cAMP
Target Epac Activator
Lipophilicity 1.69
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000