Site selective cAMP analogue with preference for site B of R I of cAMP-dependent protein kinase. In combination with 8-PIP-cAMP
(Cat. No. P 002), which selects site A of R I and site B of R II specific synergistic activation of kinase type I can be obtained. Reference: Skalhegg et al., J. Biol. Chem
, 15707 - 15714 (1992). Also suitable as a ligand in affinity chromatography (8-AHA-cAMP-Agarose
; Cat. No. A 028) or surface plasmon resonance chip technology (Herberg et al., J. Mol. Biol
, 329 - 339 (2000); Moll et al., J. Neural. Transm
, 1015 - 1032 (2006)) and for modification with fluorophores. Detailed technical information and selected references available.