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8-AHA-cAMP

8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate ( 8-AHA-cAMP )
cyclic AMP functionalized for conjugation with markers and dyes or for immobilization
Cat. No.: A 011
    
CAS No.: [39824-30-1]
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Product Name Price (net) Qty
Cat. No.: A 011-10
Unit: 10 µmol / ~4.4 mg
$77.00
Site selective cAMP analogue with preference for site B of R I of cAMP-dependent protein kinase. In combination with 8-PIP-cAMP (Cat. No. P 002), which selects site A of R I and site B of R II specific synergistic activation of kinase type I can be obtained. Reference: Skalhegg et al., J. Biol. Chem., 267, 15707 - 15714 (1992). Also suitable as a ligand in affinity chromatography (8-AHA-cAMP-Agarose; Cat. No. A 028) or surface plasmon resonance chip technology (Herberg et al., J. Mol. Biol., 298, 329 - 339 (2000); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006)) and for modification with fluorophores. Detailed technical information and selected references available.
Cat. No. A 011
CAS number [39824-30-1]
Purity > 98% HPLC
Salt form Free acid
Storage temperature -20°C / -4°F
Molecular formula C₁₆H₂₆N₇O₆P
Molecular weight [g/mol] 443,4
Modifications 8-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.34
Absorption max [nm] 273
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
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