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Alternative structural projections:

8-AHA-2'-O-Me-cAMP-Agarose

8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel
Cat. No.: A 057
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 057-06
Unit: 0.6 ml
$259.00
Cat. No.: A 057-25
Unit: 2.5 ml
$809.00
Cat. No.: A 057-60
Unit: 6 ml
$1,630.00

The second messenger cyclic AMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. Suitable for affinity chromatography of various cAMP-responsive proteins, especially those which tolerate modification of the ribose 2'-hydroxy group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available. Reference: Borland et al., Mol. Pharmacol., 69, 374 - 384 (2006).

 

Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.

Cat. No. A 057
Patent Information Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
CAS number [pending]
Storage temperature 4°C / 39°F
Modifications 8-cAMP, 2'-cAMP
  • 1. Hanke S. E., Bertinetti D., Badel A., Schweinsberg S., Genieser H.-G.Herberg F. W., N. Biotechnol., 28, 294 - 301 (2011), "Cyclic Nucleotides as Affinity Tools: Phosphorothioate cAMP Analogues Adress Specific PKA Subproteomes"
  • 2. Borland G., Gupta M., Magiera M. M., Rundell C. J., Fuld S.Yarwood S. J., Mol. Pharmacol., 69, 374 - 384 (2006), "MAP1B-LC1 Enhances Activation of Rap1 by Exchange Protein Activated by Cyclic AMP (EPAC) but not Intracellular Targeting"