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8-AET-N¹-cIDPR

8- (2- Aminoethylthio)- cyclic inosine diphosphate ribose ( 8-AET-N1-cIDPR ), sodium salt

1-cIDPR functionalized for conjugation with markers and dyes or for immobilization
Cat. No.: A 140
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 140-005
Unit: 0.5 µmol / ~309 µg
$188.00
For other salt forms or higher purity please inquire. Metabolically stable analogue of the second messenger cyclic adenosine diphosphate ribose (cADPR, Cat. No. C 005) which is suitable as a ligand in affinity chromatography or for coupling of various labelling structures including fluorophores. The parent compound N1-cIDPR (Cat. No. C 098) is offered as well. Detailed technical information available. Reference for structurally related agonistic N1-cIDPR analogues: Moreau et al., J. Med. Chem., 49, 5162 - 5176 (2006).
Cat. No. A 140
CAS number [pending]
Purity > 97 % HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₇H₂₅N₅O₁₄P₂S (free acid)
Molecular weight [g/mol] 617,4 (free acid)
Absorption max [nm] 269
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10700
UV pH value 4
  • 1. Moreau C., Wagner G. K., Weber K., Guse A. H.Potter B. V., J. Med. Chem., 49, 5162 - 5172 (2006), "Structural Determinants for N1/N7 Cyclization of Nicotinamide Hypoxanthine 5'-Dinucleotide (NHD+) Derivatives by ADP-Ribosyl Cyclase from Aplysia Californica: Ca2+-Mobilizing Activity of 8-Substituted Cyclic Inosine 5'-Diphosphoribose Analogues in T-Lymphocytes"