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Alternative structural projections:

7-CH-cGMP

7- Deazaguanosine- 3', 5'- cyclic monophosphate ( 7-CH-cGMP ), sodium salt
Cat. No.: D 099
    
CAS No.: [81611-03-2]
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Product Name Price (net) Qty
Cat. No.: D 099-05
Unit: 5 µmol / ~1.8 mg
$138.00
Cyclic GMP analogue lacking purine N-7 nitrogen for receptor mapping studies. Detailed technical information and references available. References: Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998); Quynh-Hoa et al., Angew. Chem., 94, 366 (1982).
Cat. No. D 099
CAS number [81611-03-2]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₁H₁₂N₄O₇P · Na
Molecular weight [g/mol] 366,2
Modifications 7-cGMP
Target PKG (cGK) Activator
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10600
  • 1. Abadi R. H. H. B., Anal. Biochem., 312, 91 - 100 (2003), "Nucleotide Profile of Mouse Liver: Response to 2'-O-Dibutyryl Cytidine 3',5'-Cyclic Monophosphate"
  • 2. Hebert M. C., Schwede F., Jastorff B.Cote R. H., J. Biol. Chem., 273, 5557 - 5565 (1998), "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs"
  • 3. Couchie D., Petridis G., Jastorff B.Erneux C., Eur. J. Biochem., 136, 571 - 575 (1983), "Characterization of Phosphodiesterase Catalytic Sites by Means of Cyclic Nucleotide Derivatives"
  • 4. Tran-Thi Q.-A., Franzen D.Seela F., Angew. Chem., 94, 366 - 366 (1982), "7-Desazaguanosin-3´,5´-Phosphat - ein isosteres cGMP-Analogon mit hoher Affinität zu Cyclonucleotid-Phosphodiesterase"