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7-CH-ATP

7- Deazaadenosine- 5'- O- triphosphate ( 7-CH-ATP ), sodium salt
Isosteric modification of ATP
Cat. No.: D 096
    
CAS No.: [10058-66-9]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: D 096-05
Unit: 5 µmol / ~2.5 mg
$322.00

For other salt forms or a guaranteed higher purity please inquire. Isosteric modification of ATP. Causes bending of corresponding oligonucleotides. Detailed technical information available. References: Petrescu et al., Biochemistry, 21, 886 - 893 (1982); Wieczorek et al., Bioorg. Med. Chem. Lett., 4, 987 – 994 (1994).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. D 096
CAS number [10058-66-9]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₁H₁₇N₄O₁₃P₃ (free acid)
Molecular weight [g/mol] 506,2 (free acid)
Absorption max [nm] 269
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 12000
  • 1. Wieczorek A., Dinter-Gottlieb G.Gottlieb P. A., Bioorg. Med. Chem., 4, 987 - 994 (1994), "Evidence that Total Subsitution of Adenine with 7-Deaza-adenine in the HDV Antigenomic Ribozyme Changes the Kinetics of RNA Folding"
  • 2. Wiezorek A., Dinter-Gottlieb G.Gottlieb P. A., Bioorg. Med. Chem., 4, 987 - 994 (1994), "Evidence that Total Subsitution of Adenine with 7-Deaza-adenine in the HDV Antigenomic Ribozyme Changes the Kinetics of RNA Folding"
  • 3. Petrescu I., Lascu I., Goia I., Markert M., Schmidt F. H., Deaciuc I. V., Kezdi M.Barzu O., Bio. Chem., 21, 886 - 893 (1982), "Phosphorylation and Hydrolysis of 7-Dezaadenine Nucleotides by Rat Liver and Beef Heart Mitochondria"
  • 4. Zimmerman T. P., Wolberg G.Duncan G. S., J. Biol. Chem., 253, 8792 - 8797 (1978), "Metabolism of Tubericidin and Formycin to Their 3´:5´-Cyclic Nucleotides in Mammalian Cells"