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6-Phe-ATP

N6- Phenyladenosine- 5'- O- triphosphate ( 6-Phe-ATP ), sodium salt

Cat. No.: P 015
    
CAS No.: [105740-47-4]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: P 015-05
Unit: 5 µmol / ~2.9 mg
$303.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics approach). The corresponding diphosphate (Cat. No. P 014) is offered as well. Detailed technical information available. Reference: Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. P 015
CAS number [105740-47-4]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₆H₂₀N₅O₁₃P₃ (free acid)
Molecular weight [g/mol] 583,3 (free acid)
Absorption max [nm] 288
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 20800
  • 1. Chen X., Zhao X., Abeyweera T. P.Rotenberg S. A., Biochemistry, 51, 7087 - 7097 (2012), "Analysis of Substrates of Protein Kinase C Isoforms in Human Breast Cells by the Traceable Kinase Method"
  • 2. Ulrich S. M., Kenski D. M.Shokat K. M., Biochemistry, 42, 7915 - 7921 (2003), "Engineering a 'Methionine Clamp' into Src Family Kinases Enhances Specificity toward Unnatural ATP Analogues"
  • 3. Gillespie P. G., Gillespie S. K. H., Mercer J. A., Shah K.Shokat K. M., J. Biol. Chem., 274, 31373 - 31381 (1999), "Engineering of the Myosin-Iß Nucleotide-binding Pocket to Create Selective Sensitivity to N6-modified ADP Analogs"
  • 4. Moffat L. D., Brown S. B. A., Grassie M. E., Ulke-Lemée A., Williamson L. M., Walsh M. P.MacDonald J. A., J.Biol.Chem., 286, 36978 - 36991 (0), "Chemical Genetics of Zipper-interacting Protein Kinase Reveal Myosin Light Chain as a Bona Fide Substrate in Permeabilized Arterial Smooth Muscle"