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6-Fu-ATP

N⁶- Furfuryladenosine- 5'- O- triphosphate ( 6-Fu-ATP ), sodium salt
Cat. No.: F 007
    
CAS No.: [1450894-16-2]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: F 007-05
Unit: 5 µmol / ~2.9 mg
$303.00

For other salt forms or a guaranteed higher purity please inquire. Analogue of ATP that may be useful for specific interaction with modified receptor proteins (chemical genetics approach). The corresponding diphosphate 6-Fu-ADP (Cat. No. F 006) and 6-Fu-ATP-γ-S (Cat. No. F 008) are also offered. Detailed technical information available. For information on related compounds as well as on the "chemical genetics approach" compare: Shah et al., Proc. Natl. Acad. Sci. USA, 94, 3565 - 3570 (1997); Ulrich et al., Biochemistry, 42, 7915 - 7921 (2003).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. F 007
CAS number [1450894-16-2]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₅H₂₀N₅O₁₄P₃ (free acid)
Molecular weight [g/mol] 587,3 (free acid)
Absorption max [nm] 267
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 20500
  • 1. Ulrich S. M., Kenski D. M.Shokat K. M., Biochemistry, 42, 7915 - 7921 (2003), "Engineering a 'Methionine Clamp' into Src Family Kinases Enhances Specificity toward Unnatural ATP Analogues"
  • 2. Shah K., Liu Y., Deirmengian C.Shokat K. M., Proc. Natl. Acad. Sci. USA, 94, 3565 - 3570 (1997), "Engineering Unnatural Nucleotide Specificity for Rous Sarcoma Virus Tyrosine Kinase to Uniquely Label its Direct Substrates"