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6-cHe-ATP-γ-S

N⁶- Cyclohexyladenosine- 5'- O- (3- thiotriphosphate) ( 6-cHe-ATP-γ-S ), sodium salt
NTP analogue for chemical genetics
Cat. No.: C 127
    
CAS No.: [pending]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: C 127-05
Unit: 5 µmol
$429.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics approach). 6-Bn-ATP-γ-S (Cat. No. B 072), 6-cPe-ATP-γ-S (Cat. No. C 116), 6-Fu-ATP-γ-S (Cat. No. F 008), 6-(1-MeBu)-ATP-γ-S (Cat. No. M 074) 6-Phe-ATP-γ-S (Cat. No. P 044) and 6-PhEt-ATP-γ-S (Cat. No. P 026) are available as well. Detailed technical information available. For information on related compounds as well as on the "chemical genetics approach" compare: Allen et al., J. Am. Chem. Soc., 127, 5288 - 5289 (2005); Allen et al., Nature Meth., 4, 511 - 516 (2007); Lo and Hollingsworth, Methods Mol. Biol., 745, 135 - 149 (2011).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 8.5.

Cat. No. C 127
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 8.5
Storage temperature -70°C / -94°F
Molecular formula C₁₆H₂₆N₅O₁₂P₃S (free acid)
Molecular weight [g/mol] 605,4 (free acid)
Absorption max [nm] 270
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 19900
  • 1. Lo H.-C.Hollingsworth N. M., Methods Mol. Biol., 745, 135 - 149 (2011), "Using the Semi-synthetic Epitope System to Identify Direct Substrates of the Meiosis-specific Budding Yeast Kinase, Mek1"
  • 2. Allen J. J., Li M., Brinkworth C. S., Paulson J. L., Wang D., Hübner A., Chou W.-H., Davis R. J., Burlingame A. L., Messing R. O., Katayama C. D., Hedrick S. M.Shokat K. M., Nature Methods, 4, 511 - 516 (2007), "A Semisynthetic Epitope for Kinase Substrates"
  • 3. Allen J. J., Lazerwith S. E.Shokat K. M., J. Am. Chem. Soc., 127, 5288 - 5289 (2005), "Bio-Orthogonal Affinity Purification of Direct Kinase Substrates"