0 Items - $0.00
Categories
A to Z

6-Bn-ATP-γ-S

N⁶- Benzyladenosine- 5'- O- (3- thiotriphosphate) ( 6-Bn-ATP-γ-S ), sodium salt
NTP analogue for chemical genetics
Cat. No.: B 072
    
CAS No.: [944834-42-8]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: B 072-05
Unit: 5 µmol / ~3.1 mg
$429.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics approach). 6-cPe-ATP-γ-S (Cat. No. C 116), 6-cHe-ATP-γ-S (Cat. No. C 127),6-Fu-ATP-γ-S (Cat. No. F 008), 6-(1-MeBu)-ATP-γ-S (Cat. No. M 074), 6-Phe-ATP-γ-S (Cat. No. P 044) and 6-PhEt-ATP-γ-S (Cat. No. P 026) are available as well. Detailed technical information available. References: Allen et al., Nature Meth., 4, 511 - 516 (2007) & J. Am. Chem. Soc., 127, 5288 - 5289 (2005); Blethrow et al., Proc. Nat. Acad. Sci. USA, 105, 1442 - 1447 (2008).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 8.5.

Cat. No. B 072
CAS number [944834-42-8]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 8.5
Storage temperature -70°C / -94°F
Molecular formula C₁₇H₂₂N₅O₁₂P₃S (free acid)
Molecular weight [g/mol] 613,4 (free acid)
Absorption max [nm] 269
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 20500
  • 1. Lourido S., Jeschke G. R., Turk B. E.Sibley L. D., ACS Chem. Biol., 8, 1155 - 1162 (2013), "Exploiting the Unique ATP-Binding Pocket of Toxoplasma Calcium-Dependent Protein Kinase 1 to Identify its Substrates"
  • 2. Cibrian Uhalte E., Kirchner M., Hellwig N., Allen J. J., Donat S., Shokat K. M., Selbach M.Abdelilah-Seyfried S., PLoS One, 7, 1 - 6 (2012), "In Vivo Conditions to Identify Prkci Phosphorylation Targets Using the Analog-sensitive Kinase Method in Zebrafish"
  • 3. Blasius M., Forment J. V., Thakkar N., Wagner S. A., Choudhary C.Jackson S. P., Genome Biology, 12, 0 - 0 (2011), "A Phospho-proteomic Screen Identifies Substrates of the Checkpoint Kinase Chk1"
  • 4. Blethrow J. D., Glavy J. S., Morgan D. O.Shokat K. M., Proc. Natl. Acad. Sci. USA, 105, 1442 - 1447 (2008), "Covalent Capture of Kinase-specific Phosphopeptides Reveals Cdk1-cyclin B Substrates"
  • 5. Allen J. J., Li M., Brinkworth C. S., Paulson J. L., Wang D., Hübner A., Chou W.-H., Davis R. J., Burlingame A. L., Messing R. O., Katayama C. D., Hedrick S. M.Shokat K. M., Nature Methods, 4, 511 - 516 (2007), "A Semisynthetic Epitope for Kinase Substrates"
  • 6. Allen J. J., Lazerwith S. E.Shokat K. M., J. Am. Chem. Soc., 127, 5288 - 5289 (2005), "Bio-Orthogonal Affinity Purification of Direct Kinase Substrates"