0 Items - $0.00
Categories
A to Z

6-(3-MeBn)-ATP

N6- (3- Methylbenzyl)adenosine- 5'- O- triphosphate ( 6-(3-MeBn)-ATP ), sodium salt

Analogue for chemical genetics
Cat. No.: M 025
    
CAS No.: [215321-95-2]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: M 025-05
Unit: 5 µmol / ~3.1 mg
$303.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics). The corresponding diphosphate (Cat. No. M 024) is offered as well. Detailed technical information available. References: Liu et al., Bioorg. Med. Chem., 6, 1219 – 1226 (1998); Gillespie et al., J. Biol. Chem., 274, 31373 – 31381 (1999); Liu et al., Biochemistry, 39, 14400 – 14408 (2000).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. M 025
CAS number [215321-95-2]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₈H₂₄N₅O₁₃P₃ (free acid)
Molecular weight [g/mol] 611,3 (free acid)
Absorption max [nm] 269
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 20500
  • 1. Chen X., Zhao X., Abeyweera T. P.Rotenberg S. A., Biochemistry, 51, 7087 - 7097 (2012), "Analysis of Substrates of Protein Kinase C Isoforms in Human Breast Cells by the Traceable Kinase Method"
  • 2. Liu Y., Witucki L. A., Shah K., Bishop A. C.Shokat K. M., Biochemistry, 39, 14400 - 14408 (2000), "Src-Abl Tyrosine Kinase Chimeras: Replacement of the Adenione Binding Pocket of c-Abl with v-Src to Swap Nucleotide and Inhibitor Specifities"
  • 3. Gillespie P. G., Gillespie S. K. H., Mercer J. A., Shah K.Shokat K. M., J. Biol. Chem., 274, 31373 - 31381 (1999), "Engineering of the Myosin-Iß Nucleotide-binding Pocket to Create Selective Sensitivity to N6-modified ADP Analogs"
  • 4. Liu Y., Shah K., Yang F., Witucki L.Shokat K. M., Bioorg. Med. Chem., 6, 1219 - 1226 (1998), "A Molecular Gate which Controls Unnatural ATP Analogue Recognition by the Tyrosine Kinase v-Src"