0 Items - $0.00
Categories
A to Z

6-(2-MeBu)-ATP

N6- (2- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-(2-MeBu)-ATP ), sodium salt

Cat. No.: M 029
    
CAS No.: [252889-14-8]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: M 029-05
Unit: 5 µmol / ~2.9 mg
$303.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics approach). The corresponding diphosphate (Cat. No. M 028) is offered as well. Detailed technical information available. References: Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999); Zhou et al., J. Physiology, 569, 447 - 457 (2005).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. M 029
CAS number [252889-14-8]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₅H₂₆N₅O₁₃P₃ (free acid)
Molecular weight [g/mol] 577,3 (free acid)
Absorption max [nm] 268
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Zhou Z., Wang X., Li M., Sohma Y., Zou X.Hwang T.-C., J. Physiol., 569, 447 - 457 (2005), "High Affinity ATP/ADP Analogues as New Tools for Studying CFTR Gating"
  • 2. Hindley A. D., Park S., Wang L., Shah K., Wang Y., Hu X., Shokat K. M., Kolch W., Sedivy J. M.Yeung K. C., FEBS Lett., 556, 26 - 34 (2004), "Engineering the Serine/Threonine Protein Kinase Raf-1 to Utilize an Orthogonal Analogue of ATP Substituted at the N6 Position"
  • 3. Gillespie P. G., Gillespie S. K. H., Mercer J. A., Shah K.Shokat K. M., J. Biol. Chem., 274, 31373 - 31381 (1999), "Engineering of the Myosin-Iß Nucleotide-binding Pocket to Create Selective Sensitivity to N6-modified ADP Analogs"
  • 4. Moffat L. D., Brown S. B. A., Grassie M. E., Ulke-Lemée A., Williamson L. M., Walsh M. P.MacDonald J. A., J.Biol.Chem., 286, 36978 - 36991 (0), "Chemical Genetics of Zipper-interacting Protein Kinase Reveal Myosin Light Chain as a Bona Fide Substrate in Permeabilized Arterial Smooth Muscle"