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5'-TMPS

Thymidine- 5'- O- monophosphorothioate ( 5'-TMPS ), sodium salt
Cat. No.: T 004
    
CAS No.: [15548-51-3]
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Product Name Price (net) Qty
Cat. No.: T 004-05
Unit: 5 µmol / ~1.6 mg
$190.00
Potential substrate, competitive inhibitor or regulator of enzymes that interact with thymidine-5'-monophosphate. Can be modified with SH-reactive reporters or linked to structures with SH-groups via a disulfide bond. Detailed technical information available. Reference: Golos et al., Biol. Chem., 382, 1439 – 1445 (2001).
Cat. No. T 004
CAS number [15548-51-3]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₅N₂O₇PS (free acid)
Molecular weight [g/mol] 338,3 (free acid)
Absorption max [nm] 267
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 9600
  • 1. Golos B., Dzik J. M., Kazimierczuk Z., Ciesla J., Zielinski Z., Jankowska J., Kraszewski A., Stawinski J., Rode W.Shugar D., Biol. Chem., 382, 1439 - 1445 (2001), "Interaction of Thymidylate Synthase with the 5'-Thiophosphates, 5'-Dithiophosphates, 5'-H-Phosphonates and 5'-S-Thiosulfates of 2'-Deoxyuridine, Thymidine and 5-Fluoro-2'-Deoxyuridine"
  • 2. Vosberg H.-P.Eckstein F., J. Biol. Chem., 257, 6595 - 6599 (1982), "Effect of Deoxynucleoside Phosphorothioates Incorporated in DNA on Cleavage by Restriction Enzymes"
  • 3. Eckstein F.Sternbach H., Biochim. Biophys. Acta, 146, 618 - 619 (1967), "Nucleoside 5'-O-Phosphorothioates as Inhibitors for Phosphatases"