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5'-GMPS

Guanosine- 5'- O- monophosphorothioate ( 5'-GMPS ), sodium salt
Cat. No.: G 018
    
CAS No.: [76310-16-2]
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Product Name Price (net) Qty
Cat. No.: G 018-10
Unit: 10 µmol / ~3.8 mg
$190.00
Substrate, competitive inhibitor or regulator of enzymes that interact with guanosine-5'-monophosphate. Can be modified with SH-reactive reporters or linked to structures with SH-groups via a disulfide bond. Detailed technical information and reference list available. References: Macosko et al., RNA, 5, 1158 - 1166 (1999); Wu et al., Bioconjugate Chem., 12, 842 - 844 (2001).
Cat. No. G 018
CAS number [76310-16-2]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₄N₅O₇PS (free acid)
Molecular weight [g/mol] 379,3 (free acid)
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14300
  • 1. Yu L. E.Koslowsky D. J., RNA, 12, 1050 - 1060 (2006), "Interactions of mRNAs and gRNAs Involved in Trypanosome Mitochondrial RNA bound to its Cognate mRNA"
  • 2. Mhlanga M. M., Vargas D. Y., Fung C. W., Kramer F. R.Tyagi S., Nucl. Acid. Res., 33, 1902 - 1912 (2005), "tRNA-linked Molecular Beacons for Imaging mRNAs in the Cytoplasm of Living Cells"
  • 3. Wu C.-W., Eder P. S., Gopalan V.Behrman E. J., Bioconjugate Chem., 12, 842 - 844 (2001), "Kinetics of Coupling Reactions That Generate Monothiophosphate Disulfides: Implications for Modification of RNAs"
  • 4. Sengle G., Jenne A., Arora P. S., Seelig B., Nowick J. S., Jäschke A.Famulok M., Bioorg. Med. Chem., 8, 1317 - 1329 (2000), "Synthesis, Incorporation Efficiency, and Stability of Disulfide Bridged Functional Groups at RNA 5´-Ends"
  • 5. Macosko J. C., Pio M. S., Tinoco I.Shin Y.-K., RNA, 5, 1158 - 1166 (1999), "A novel 5 displacement spin-labeling technique for electron paramagnetic resonance spectroscopy of RNA"