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Alternative structural projections:

4-N-cBIMP

4- Nitrobenzimidazole riboside- 3', 5'- cyclic monophosphate ( 4-NO2-cBIMP ), sodium salt
Analogue for cyclic AMP receptor mapping
Cat. No.: N 007
    
CAS No.: [127634-21-3]
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Product Name Price (net) Qty
Cat. No.: N 007-05
Unit: 5 µmol / ~1.9 mg
$248.00
For other salt forms or metabolites please inquire. Analogue of the second messenger cyclic AMP, lacking the purine ring nitrogens and offering a changed interaction potential at position 6 (adenine nomenclature). Suitable for receptor mapping studies. Detailed technical information available. References: Van Lookeren Campagne et al., J. Biol. Chem., 265,  5847 – 5854 (1990); Genieser et al., Carbohydr. Res., 234, 217 - 235 (1992).
Cat. No. N 007
CAS number [127634-21-3]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₂H₁₁N₃O₈P · Na
Molecular weight [g/mol] 379,2
Modifications 1-cAMP, 3-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.72
Absorption max [nm] 314
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 7500
  • 1. Rodriguez-Collazo P., Snyder S. K., Chiffer R. C., Bressler E. A., Voss T. C., Anderson E. P., Genieser H.-G.Smith C. L., Exp. Cell Res., 314, 2855 - 2869 (2008), "cAMP Signaling Regulates Histone H3 Phosphorylation and Mitotic Entry Through a Disruption of G2 Progression"
  • 2. Genieser H.-G., Winkler E., Butt E., Zorn M., Schulz S., Iwitzki F., Störmann R., Jastorff B., Doeskeland S. O., Oegreid D., Ruchaud S.Lanotte M., Carbohydr. Res., 234, 217 - 235 (1992), "Derivates of 1-ß-D-Ribofuranosylbenzimidazole 3', 5'-phosphate that Mimic the Actions of Adenosine 3', 5',- phosphate (cAMP) and Guanosine 3', 5'- phosphate (cGMP)"
  • 3. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B., Winkler E., Genieser H.-G.Kessin R. W., J. Biol. Chem., 265, 5847 - 5854 (1990), "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues"