Alternative structural projections:
For other salt forms or metabolites please inquire. Analogue of the second messenger cyclic AMP, lacking the purine ring nitrogens and offering a changed interaction potential at position 6 (adenine nomenclature). Suitable for receptor mapping studies. Detailed technical information available. References: Van Lookeren Campagne et al., J. Biol. Chem., 265, 5847 – 5854 (1990); Genieser et al., Carbohydr. Res., 234, 217 - 235 (1992).
| Cat. No. | N 007 |
| CAS number | [127634-21-3] |
| Purity | > 98% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₂H₁₁N₃O₈P · Na |
| Molecular weight [g/mol] | 379.2 |
| Modifications | 1-cAMP, 3-cAMP |
| Target | PKA (cAK) Activator |
| Lipophilicity | 1.72 |
| Absorption max [nm] | 314 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 7500 |
- 1. Rodriguez-Collazo P., Snyder S. K., Chiffer R. C., Bressler E. A., Voss T. C., Anderson E. P., Genieser H.-G.Smith C. L., Exp. Cell Res., 314, 2855 - 2869 (2008), "cAMP Signaling Regulates Histone H3 Phosphorylation and Mitotic Entry Through a Disruption of G2 Progression"
- 2. Genieser H.-G., Winkler E., Butt E., Zorn M., Schulz S., Iwitzki F., Störmann R., Jastorff B., Doeskeland S. O., Oegreid D., Ruchaud S.Lanotte M., Carbohydr. Res., 234, 217 - 235 (1992), "Derivates of 1-ß-D-Ribofuranosylbenzimidazole 3', 5'-phosphate that Mimic the Actions of Adenosine 3', 5',- phosphate (cAMP) and Guanosine 3', 5'- phosphate (cGMP)"
- 3. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B., Winkler E., Genieser H.-G.Kessin R. W., J. Biol. Chem., 265, 5847 - 5854 (1990), "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues"
