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3'-NH₂-ATP

3'- Amino- 3'- deoxyadenosine- 5'- O- triphosphate ( 3'-NH₂-ATP )
Cat. No.: A 114
    
CAS No.: [4209-30-7]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: A 114-05
Unit: 5 µmol / ~2.5 mg
$300.00

For other salt forms or a guaranteed higher purity please inquire. Putative RNA polymerase inhibitor, ligand for affinity chromatography and suitable for modification with fluorophores and other markers. Detailed technical information available. References: Truman & Klenow, Mol. Pharmacol., 4, 77 - 86 (1968); Fraser & Rich, Proc. Nat. Acad. Sci. USA, 70, 2671 - 2675 (1973); Kinoshita & Nishigaki, J. Biochem., 122, 205 - 211 (1997).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. A 114
CAS number [4209-30-7]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₇N₆O₁₂P₃ (free acid)
Molecular weight [g/mol] 506,2 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
  • 1. Kinoshita Y.Nishigaki K., J. Biochem., 122, 205 - 211 (1997), "Unexpectedly General Replaceability of ATP in ATP-Requiring Enzymes"
  • 2. Armstrong V. W.Eckstein F., Eur. J. Biochem, 70, 30 - 38 (1976), "Interaction of Substrate Analogues with Escheria Coli DNA-Dependent RNA Polymerase"
  • 3. Fraser T. H.Rich A., Proc. Nat. Acad. Sci. USA, 70, 2671 - 2675 (1973), "Synthesis and Aminoacylation of 3'-Amino-3'-deoxy Transfer RNA and Its Activity in Ribosomal Protein Synthesis"
  • 4. Truman J. T.Klenow H., Mol. Pharmacol., 4, 77 - 86 (1968), "Effect of 3'-Amino-3'-deoxyadenosine on Nucleic Acid Synthesis in Ehrlich Ascites Tumor Cells"