0 Items - $0.00
Categories
A to Z

Alternative structural projections:

2'-O-MS-cGMP

2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate, free acid ( 2'-O-MS-cGMP )
Immobilizable cyclic GMP
Cat. No.: M 015
    
CAS No.: [39118-26-8]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: M 015-25
Unit: 25 µmol / ~12 mg
$192.00
2'-O-MS-cGMP in this free acid form is soluble in organic solvents such as dimethylformamide (DMF). For other salt forms please inquire. Cyclic GMP analogue, suitable for coupling of various ligands including proteins for ELISA. For a structure with a hydrolytically and enzymatically much more stable linkage please compare 2'-AHC-cGMP (Cat. No. A 048). Detailed technical information available. Reference: Dressendoerfer et al., J. Immunoassay, 16, 37 - 53 (1995).
Cat. No. M 015
CAS number [39118-26-8]
Purity > 98% HPLC
Salt form Free acid
Storage temperature -20°C / -4°F
Molecular formula C₁₄H₁₆N₅O₁₀P
Molecular weight [g/mol] 445,3
Modifications 2'-cGMP
Lipophilicity 1.00
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13500
  • 1. Jäger R., Russwurm C., Schwede F., Genieser H.-G., Koesling D.Russwurm M., J. Biol. Chem., 287, 1210 - 1219 (2012), "Activation of PDE10 and PDE11 Phosphodiesterases"
  • 2. Horton J. K., Smith L., Ali A., Baxendale P. M., Neumann K.Kolb A., Packard Instrument Company, 0, 0 - 0 (2000), "High Throughput Screening for cAMP Formation by Scintillation Proximity Radioimmunoassay"
  • 3. Dressendoerfer R. A., Heim J.-M., Gerzer R.Strasburger C. J., J. Immunoassay, 16, 37 - 53 (1995), "A Non-isotopic Immunoassay for Guanosine 3'5' - Cyclic Monophosphate Using a Cyclic GMP-biotin Conjugate as Tracer"
  • 4. Horton J. K., Martin R. C., Kalinka S., Cushing A., Kitcher J. P., O'Sullivan M. J.Baxendale P. M., J. Immunol. Method., 155, 31 - 40 (1992), "Enzyme Immunoassays for the Estimation of Adenosine 3',5' Cyclic Monophosphate in Biological Fluids"
  • 5. Sugiyama K., Takada K.Yamamoto I., European Patent Application Filing date 10.08.87, 87111542, 1 - 36 (1987), "Cosmetic Agent for Application to Skin"
  • 6. Erneux C., Couchie D., Dumont J. E., Baraniak J., Stec W. J., Garcia Abbad E., Petridis G.Jastorff B., Eur. J. Biochem., 115, 503 - 510 (1981), "Specificity of cyclic GMP Activation of a Multi-substrate Cyclic Nucleotide Phosphodiesterase from Rat Liver"
  • 7. Francis S. H., Lincoln T. M.Corbin J. D., J. Biol. Chem., 255, 620 - 626 (1980), "Characterization of a Novel cGMP Binding Protein from Rat Lung"
  • 8. Cailla H. L., Roux D., Kuntziger H.Delaage M. A., Hormones and Cell Regulation, 4, 1 - 25 (1980), "Antibodies Against Cyclic AMP, Cyclic GMP and Cyclic CMP. Their Use in High Performance Radioimmunoassay."
  • 9. Nishikori K.Maeno H., J. Biol. Chem., 254, 6099 - 6109 (1979), "Close Relationship between Adenosine 3',5'-Monophosphate-dependent Endogenous Phosphorylation of a Specific Protein and Stimulation of Calcium Uptake in Rat Uterine Microsomes"
  • 10. Steiner A. L., Parker C. W.Kipnis D. M., J. Biol. Chem., 247, 1106 - 1113 (1972), "Radioimmunoassay for Cyclic Nucleotides. I. Preparation of Antibodies and Iodinated Cyclic Nucleotides"