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Alternative structural projections:

2'-Fluo-AHC-c-diGMP

2'- O- (6- [Fluoresceinyl]aminohexylcarbamoyl)- cyclic diguanosine monophosphate ( 2'-Fluo-AHC-c-diGMP ), sodium salt
Fluorescent analogue of c-diGMP
Cat. No.: F 009
    
CAS No.: [1422761-55-4]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: F 009-001
Unit: 0.1 µmol / ~0.1 mg
$330.00

For other salt forms please inquire. Fluorescent analogue of the bacterial second messenger c-diGMP (Cat. No. C 057) with λexc 494 nm and λem 517 nm. The dye is conjugated via a 9 atom spacer to one of the 2'-hydroxy groups. Detailed technical information available. Reference: Düvel et al., J. Microbiol. Methods., 88, 229 - 236 (2012).

Cat. No. F 009
CAS number [1422761-55-4]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₄₈H₄₈N₁₂O₂₁P₂ (free acid)
Molecular weight [g/mol] 1190.9 (free acid)
Excitation max [nm] 494
Emission max [nm] 517
Absorption max [nm] 494
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] ~79000
UV pH value 9
  • 1. Sundriyal A. S., Massa C., Samoray D., Zehender F., Sharpe T., Jenal U.Schirmer T., J. Biol. Chem., 289, 6978 - 6990 (2014), "Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP"
  • 2. Kim S., Li L., Maliga Z., Yin Q., Wu H.Mitchison T. J., ACS Chem. Biol., 8, 1396 - 1401 (2013), "Anti-cancer Flavonids are Mouse Selective STING Agonists"
  • 3. Düvel J., Bertinetti D., Möller S., Schwede F., Morr M., Wissing J., Radamm L., Zimmermann B., Genieser H.-G., Jänsch L., Herberg F. W.Häussler S., J. Microbiol. Methods., 88, 229 - 236 (2012), "A Chemical Proteomics Approach to Identify c-di-GMP Binding Proteins in Pseudomonas Aeruginosa"