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2'-[DY-547]-AHC-c-diGMP

2'- O- (6- [DY-547]- aminohexylcarbamoyl)- cyclic diguanosine monophosphate ( 2'-[DY-547]-AHC-c-diGMP / cdGMPDY547 ), sodium salt

Fluorescent analogue of c-diGMP
Cat. No.: D 116
    
CAS No.: [pending]
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Product Name Price (net) Qty
Cat. No.: D 116-001
Unit: 0.1 µmol / ~0.1 mg
$300.00

For other salt forms please inquire. Fluorescent analogue of the bacterial second messenger c-diGMP (Cat. No. C 057); λexc 557 nm, λem 574 nm. The DY-547 dye is connected to one of the ribose 2'-hydroxy groups of c-diGMP via a 9 atom spacer. Detailed technical information available. Reference: Hanson et al., J. Clin. Invest., 125, 2532 - 2546 (2015).

Cat. No. D 116
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₅₇H₇₁N₁₄O₂₂P₂S₂ · Na (free acid nucleotide)
Molecular weight [g/mol] 1453.3 (free acid nucleotide)
Excitation max [nm] 557
Emission max [nm] 574
Absorption max [nm] 559
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 150000
Solvent for UV data EtOH
  • 1. Hanson M. C., Crespo M. P., Abraham W., Moynihan K. D., Szeto G. L., Chen S. H., Melo M. B., Mueller S.Irvine D. J., J.Clin.Invest., 125, 2532 - 2546 (2015), "Nanoparticulate STING Agonists are Potent Lymph Node-targeted Vaccine Adjuvants"