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2-Cl-Ade

2- Chloroadenine ( 2-Cl-Ade )
 
Cat. No.: C 040
    
CAS No.: [1839-18-5]
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Product Name Price (net) Qty
Cat. No.: C 040-10
Unit: 10 µmol / ~1.7 mg
$110.00
Potential cytotoxic metabolite of Cladribine (Cat. No. C 028), Clofarabine, 2-Cl-cAMP (Cat. No. C 020) and 2- chloroadenosine (Cat. No. C 017), respectively. Detailed technical information available. Reference: Bontemps et al., Biochem Pharmacol., 59, 1237 - 1243 (2000).
Cat. No. C 040
CAS number [1839-18-5]
Purity > 95% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₅H₄ClN₅
Molecular weight [g/mol] 169,6
Absorption max [nm] 263
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14000
  • 1. Chevassus H., Roig A., Belloc C., Lajoix A. D., Broca C., Manteghetti M.Petit P., Naunyn-Schmiedebergs Arch. Pharmacol., 366, 464 - 469 (2002), "P2Y Receptor Activation Enhances Insulin Release from Pancreatic Beta-cells by Triggering the Cyclic AMP/Protein Kinase A Pathway"
  • 2. Bontemps F., Delacauw A., Cardoen S., Van Den Neste E.Van den Berghe G., Biochem Pharmacol., 59, 1237 - 1243 (2000), "Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2'-deoxyadenosine"