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Alternative structural projections:

2-Cl-8-MA-cAMP

2- Chloro- 8- methylaminoadenosine- 3', 5'- cyclic monophosphate ( 2-Cl-8-MA-cAMP ), sodium salt
Site B I-selective analogue for synergistic activation of PKA I
Cat. No.: C 080
    
CAS No.: [96990-16-8]
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Product Name Price (net) Qty
Cat. No.: C 080-05
Unit: 5 µmol / ~2.1 mg
$248.00
For other salt forms please inquire. Cyclic AMP analogue with high selectivity for site B I of PKA. Combined with A I-selective analogues synergistic activation of PKA type I is achieved. Detailed technical information available. Reference: Krakstad et al., J. Leukocyte Biol., 76, 641 - 647 (2004).
Cat. No. C 080
CAS number [96990-16-8]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₁H₁₃ClN₆O₆P · Na
Molecular weight [g/mol] 414,7
Modifications 2-cAMP, 8-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.43
Absorption max [nm] 279
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16600
  • 1. Krakstad C., Chua N. H.Doeskeland S. O., J. Leukoc. Biol., 76, 641 - 647 (2004), "cAMP Protects Neutrophils against TNF-Alpha-induced Apoptosis by Activation of cAMP-dependent Protein Kinase, Independently of Exchange Protein Directly Activated by cAMP (EPAC)"