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Alternative structural projections:

2'-Biotin-16-c-diAMP

2'- O- (6- (6- [Biotinyl]aminohexanoyl)aminohexylcarbamoyl)- cyclic diadenosine monophosphate ( 2'-Biotin-16-c-diAMP / 2'-[Biotin]-AHC-c-diAMP ), sodium salt

Biotinylated analogue of the bacterial second messenger c-diAMP
Cat. No.: B 106
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: B 106-001
Unit: 0.1 µmol / ~0.1 mg
$273.00

For other salt forms please inquire. 2'-Biotin-16-c-diAMP is an analogue of the bacterial second messenger c-diAMP (Cat. No. C 088) in which a biotin moiety has been attached to the 2'-hydroxy group of one ribose via a 16 atom spacer. Potential tracer in immunoassays, for affinity chromatography or pull-down assays. Detailed technical information available. Reference: Corrigan et al., Proc. Natl. Acad. Sci. USA, 110, 9084 - 9089 (2013).

Cat. No. B 106
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₄₃H₆₃N₁₅O₁₆P₂S (free acid)
Molecular weight [g/mol] 1140,1 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 27000
  • 1. Gundlach J., Dickmanns A., Schröder-Tittmann K., Neumann P., Kaesler J., Kampf J., Herzberg C., Hammer E., Schwede F., Kaever V., Tittmann K., Stülke J.Ficner R., J.Biol.Chem., 290, 3069 - 3080 (2015), "Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA"
  • 2. Corrigan R. M., Campeotto I., Jeganathan T., Roelofs K. G., Lee V. T.Gründling A., Proc. Natl. Acad. Sci. USA, 110, 9084 - 9089 (2013), "Systematic Identification of Conserved Bacterial c-di-AMP Receptor Proteins"
  • 3. Bai Y., Yang J., Eisele L. E., Underwood A. J., Koestler B. J., Waters C. M., Metzger D. W.Bai G., Journal of Bacteriology, 195, 5123 - 5132 (2013), "Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence"